FMoc-a-allyl-D-Gly-OH - Names and Identifiers
Name | (R)-N-Fmoc-Allylglycine
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Synonyms | Fmoc-D-Algly-Oh Fmoc-allyl-Gly-OH FMoc-R-allyglycine Fmoc-D-Allylglycine Fmoc-Allyl-D-Glycine Fmoc-D-Gly(Allyl)-Oh Fmoc-D-(Allyl)Gly-Oh FMoc-a-allyl-D-Gly-OH Fmoc-D-2-Allylglycine Fmoc-Alpha-Allyl-D-Gly (R)-N-Fmoc-Allylglycine Fmoc-(R)-2-Allylglycine Fmoc-(R)-2-Amino-4-Pentenoic Acid FMOC-D-2-allylglycine Hydrochloride FMoc-D-Allyglycine FMoc-D-Allyglycine (R)-2-FMoc-aMino-4-pentenoic acid, FMoc-D-allylglycine (2R)-2-{[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino}Pent-4-Enoate
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CAS | 170642-28-1
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InChI | InChI=1/C20H19NO4/c1-2-7-18(19(22)23)21-20(24)25-12-17-15-10-5-3-8-13(15)14-9-4-6-11-16(14)17/h2-6,8-11,17-18H,1,7,12H2,(H,21,24)(H,22,23)/p-1/t18-/m1/s1 |
FMoc-a-allyl-D-Gly-OH - Physico-chemical Properties
Molecular Formula | C20H19NO4
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Molar Mass | 337.37 |
Density | 1.2486 (rough estimate) |
Melting Point | 134 °C |
Boling Point | 473.68°C (rough estimate) |
Flash Point | 294.3°C |
Vapor Presure | 1.64E-13mmHg at 25°C |
Appearance | White granular powder |
BRN | 7389283 |
pKa | 3.72±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.5800 (estimate) |
MDL | MFCD01311776 |
Physical and Chemical Properties | Storage Conditions: Store at 0 ℃ |
FMoc-a-allyl-D-Gly-OH - Risk and Safety
Hazard Symbols | Xi - Irritant
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Safety Description | S24/25 - Avoid contact with skin and eyes.
S22 - Do not breathe dust.
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WGK Germany | 3 |
HS Code | 29242990 |
Hazard Class | IRRITANT |
FMoc-a-allyl-D-Gly-OH - Introduction
(R)-N-Fmoc-Allylglycine is an organic compound with specific properties and uses. The following is a description of its nature, use, preparation and safety information:
Nature:
(R)-N-Fmoc-Allylglycine is a protected amino acid and is often used as a precursor for amino acid derivatives in organic synthesis. It is a white crystalline solid with good solubility. It can be identified by techniques such as nuclear magnetic resonance (NMR).
Use:
(R)-N-Fmoc-Allylglycine are mainly used in solid phase synthesis. It can be obtained by chemical synthesis or biosynthesis, and then introduced into the target molecule in the form of a protecting group. After deprotection, it can be used as a substitute for natural amino acids, participate in peptide synthesis reactions, and be used in drug design and biomedical research.
Method:
(R)-N-Fmoc-Allylglycine are usually prepared by chemical synthesis. First, D-allylglycine is reacted with Fmoc-Cl (dimethyltetrahydrofuran deprotection reagent) to form (R)-N-Fmoc-Allylglycine. The reaction conditions and specific process can be adjusted according to actual needs.
Safety Information:
(R)-N-Fmoc-Allylglycine has good stability under general operating conditions, but still need to pay attention to some safety matters. It should avoid contact with skin and eyes during use and storage to prevent inhalation or swallowing. Wear protective gloves, goggles and protective clothing during operation. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical attention.
Summary:
(R)-N-Fmoc-Allylglycine is a commonly used protected amino acid derivative, which has important application value in peptide synthesis. The preparation method mainly uses chemical synthesis, but it is necessary to pay attention to safety matters during operation to avoid harm to personal safety and the environment.
Last Update:2024-04-09 21:32:38