Fmoc-PEG-AA,FMOC-NH-PEG-COOH
Fmoc-PEG-AA,FMOC-NH-PEG-COOH
CAS:
Molecular Formula:
Fmoc-PEG-AA,FMOC-NH-PEG-COOH - Names and Identifiers
| Name | Fmoc-PEG-AA,FMOC-NH-PEG-COOH |
| Synonyms | Fmoc-PEG-AA,FMOC-NH-PEG-COOH |
Fmoc-PEG-AA,FMOC-NH-PEG-COOH - Physico-chemical Properties
| Storage Condition | -20℃ |
Fmoc-PEG-AA,FMOC-NH-PEG-COOH - Introduction
Fmoc-PEG-AA,FMOC-NH-PEG-COOH(Fmoc-PEG-AA,FMOC-NH-PEG-COOH) is a compound that has the following properties:
1. Molecular structure: Fmoc-PEG-AA is a polymer composed of polyethylene glycol (PEG) and amino acids (AA). The PEG in the molecular structure provides water solubility and biocompatibility, and the amino acid moiety provides specific chemical and biological properties to the compound.
2. Functionalization: The Fmoc-PEG-AA usually has a protecting group Fmoc (strong). The Fmoc protection group can protect amino acid residues to allow for selective reactions during synthesis.
3. solubility: Fmoc-PEG-AA soluble in water and some organic solvents (such as dimethyl sulfoxide and dichloromethane).
Fmoc-PEG-AA,FMOC-NH-PEG-COOH has a wide range of applications in biochemistry and materials science:
1. Peptide synthesis: Fmoc-PEG-AA can be used as a scaffold material for polypeptides, used to construct links between amino acid residues, and protect unreacted amino acids.
2. Drug delivery system: Due to its biocompatibility and regulability, Fmoc-PEG-AA can be used as a carrier for drug delivery systems. It can control the release rate and targeting of drugs and improve the efficacy of drugs.
3. Biosensors: Fmoc-PEG-AA plays a key role in biosensors. It can be used as a basic scaffold for materials to build the structure of biosensors and provide specific functionalization sites.
The method of preparing Fmoc-PEG-AA usually involves the following steps:
1. Synthesis of polyethylene glycol chain: First, the Fmoc chemical protecting group is introduced into the hydroxyl group on the polyethylene glycol chain. This typically requires the use of reactive Fmoc acid chlorides or Fmoc anhydrides.
2. Reactive amino acid: An amino acid with a corresponding protecting group is introduced into the free hydroxyl group of the Fmoc-PEG chain. This typically requires the use of a condensing agent such as activated DCC or DIC for the reaction.
3. deprotection: the Fmoc protecting group can be removed by acidic or basic conditions to obtain the Fmoc-PEG-AA final product. This will expose the amino acid residue and allow for further reactions.
When using the Fmoc-PEG-AA, you need to pay attention to the following safety information:
1. prevent inhalation: should avoid inhalation of Fmoc-PEG-AA powder or solution. Wear suitable respiratory protection during operation.
2. Avoid contact with skin and eyes: Try to avoid direct contact between Fmoc-PEG-AA and skin or eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
3. Storage and handling: When storing the Fmoc-PEG-AA, keep it dry, sealed, and place it away from heat and fire sources. In the process of treatment, should pay attention to dust and fire prevention measures.
1. Molecular structure: Fmoc-PEG-AA is a polymer composed of polyethylene glycol (PEG) and amino acids (AA). The PEG in the molecular structure provides water solubility and biocompatibility, and the amino acid moiety provides specific chemical and biological properties to the compound.
2. Functionalization: The Fmoc-PEG-AA usually has a protecting group Fmoc (strong). The Fmoc protection group can protect amino acid residues to allow for selective reactions during synthesis.
3. solubility: Fmoc-PEG-AA soluble in water and some organic solvents (such as dimethyl sulfoxide and dichloromethane).
Fmoc-PEG-AA,FMOC-NH-PEG-COOH has a wide range of applications in biochemistry and materials science:
1. Peptide synthesis: Fmoc-PEG-AA can be used as a scaffold material for polypeptides, used to construct links between amino acid residues, and protect unreacted amino acids.
2. Drug delivery system: Due to its biocompatibility and regulability, Fmoc-PEG-AA can be used as a carrier for drug delivery systems. It can control the release rate and targeting of drugs and improve the efficacy of drugs.
3. Biosensors: Fmoc-PEG-AA plays a key role in biosensors. It can be used as a basic scaffold for materials to build the structure of biosensors and provide specific functionalization sites.
The method of preparing Fmoc-PEG-AA usually involves the following steps:
1. Synthesis of polyethylene glycol chain: First, the Fmoc chemical protecting group is introduced into the hydroxyl group on the polyethylene glycol chain. This typically requires the use of reactive Fmoc acid chlorides or Fmoc anhydrides.
2. Reactive amino acid: An amino acid with a corresponding protecting group is introduced into the free hydroxyl group of the Fmoc-PEG chain. This typically requires the use of a condensing agent such as activated DCC or DIC for the reaction.
3. deprotection: the Fmoc protecting group can be removed by acidic or basic conditions to obtain the Fmoc-PEG-AA final product. This will expose the amino acid residue and allow for further reactions.
When using the Fmoc-PEG-AA, you need to pay attention to the following safety information:
1. prevent inhalation: should avoid inhalation of Fmoc-PEG-AA powder or solution. Wear suitable respiratory protection during operation.
2. Avoid contact with skin and eyes: Try to avoid direct contact between Fmoc-PEG-AA and skin or eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
3. Storage and handling: When storing the Fmoc-PEG-AA, keep it dry, sealed, and place it away from heat and fire sources. In the process of treatment, should pay attention to dust and fire prevention measures.
Last Update：2024-04-09 21:21:28
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Product Name: Fmoc-PEG-AA,FMOC-NH-PEG-COOH Visit Supplier Webpage Request for quotationTel: 18301782025
Email: 3008007409@qq.com
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Multiple Specifications
Product Name: Fmoc-PEG-AA,FMOC-NH-PEG-COOH Visit Supplier Webpage Request for quotationTel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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