Molecular Formula | C24H40O5 |
Molar Mass | 408.5714 |
Storage Condition | Room Temprature |
MDL | MFCD00130641 |
Physical and Chemical Properties | Chemical yellow-green powder with partial sweet and bitter taste and unpleasant taste. Soluble in water and ethanol. |
Use | Use of surfactants. |
storage conditions | Store at RT. |
solubility | 1150g/l |
morphology | dried, unfractionated |
PH value | 5.5-7.5 (50g/l, H2O, 20℃) |
EPA chemical information | Bile, extract (8008-63-7) |
introduction
the gall or bile of cattle, cattle or buffalo. It has the effects of clearing the liver and improving eyesight, promoting gallbladder and intestines, detoxifying and reducing swelling. The fresh bovine gallbladder is kidney-shaped, about 18-20cm long and 5-6cm wide at its widest point. After drying, it is cystic with longitudinal wrinkles. Fresh bile is greenish brown or dark brown slightly transparent liquid, slightly sticky, slightly dry becomes thick.
use
Niu Dan clears the liver and improves eyesight, promotes gallbladder and intestines, detoxifies and reduces swelling, treats wind-heat, eye diseases, jaundice, constipation, diabetes, children's convulsion, carbuncle and hemorrhoids.
Bovine bile is an effective natural wetting agent that can be used with watercolor pigments to promote flow. Cattle bile is also used for marbling, engraving, lithography and textile dyeing. It has been used as a plasticizer in mucilage mixtures.
identification test
positive sodium test (IT-28).
1:10 ethanol sample solution and iodine test solution (TS-124)0.5ml mixed, should appear blue.
content analysis
standard solution accurately weigh a certain amount of USP cholic acid reference standard, and prepare 0.5 mg/ml standard solution with 60% acetic acid. If refrigerated, it can be used for several months.
sample solution is prepared to accurately weigh about 50mg of sample, dissolve it in 100ml of 60% acetic acid solution, and mix it. Filter and discard 10ml of primary filtrate.
operation takes 1.0ml of standard solution and ml of sample solution and moves them into two-part high container respectively. In each container, 1.0ml of newly prepared 1:100 furfural solution was added. Cool the container in an ice bath for 5min. Each add 13ml of dilute sulfuric acid solution obtained by carefully adding 50ml of sulfuric acid and 65ml of water. After mixing, keep it in 70 ℃ water bath for 10min. Then immediately put in the ice bath for 2min. Use a 1cm absorption cell to measure the absorbance at 650nm in a spectrophotometer, and then calculate the cholic acid content (mg) in the sample according to the following formula:
Toxicity
GRAS(FDA & sect;184.1560,2000).
use limited
GMP; Cheese 0.002%(FDA,& sect;184.1560,2000).
production method
bovine bile is concentrated, extracted with ethanol, and then evaporated to obtain the purified part of bovine bile.