H-ORN(CBZ)-OH - Names and Identifiers
H-ORN(CBZ)-OH - Physico-chemical Properties
Molecular Formula | C13H18N2O4
|
Molar Mass | 266.29 |
Density | 1.234±0.06 g/cm3(Predicted) |
Melting Point | 209-210 °C(Solv: water (7732-18-5)) |
Boling Point | 489.4±45.0 °C(Predicted) |
Water Solubility | Soluble in 0.1N NaOG (1 mg/ml-clear, colorless solution). Slightly soluble in water. |
Solubility | Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly) |
Appearance | Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly) |
Color | White |
pKa | 3.83±0.21(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
H-ORN(CBZ)-OH - Upstream Downstream Industry
H-ORN(CBZ)-OH - Introduction
Z-ORN-OH(Z-ORN-OH) is an organic compound with the following properties:
1. Appearance: the Z-ORN-OH is white crystal or crystalline powder.
2. Solubility: It is soluble in common organic solvents (such as chloroform, dimethylformamide), but its solubility in water is low.
3. Melting Point: the melting point range of Z-ORN-OH is between 154-158 ℃.
4. Molecular formula: its chemical formula is C16H18N2O4, relative molecular mass is 310.32.
Z-ORN-OH is mainly used as an amine protective agent in the process of organic synthesis, and can be used to protect amino acids and other amine compounds. It serves to protect the amino group from unwanted side reactions in the reaction, while also increasing the selectivity of the reaction. Therefore, it is widely used in the field of peptide synthesis and drug development in organic synthesis.
Z-ORN-OH can be synthesized by the following methods:
1. The purified ornithine reacts with sulfur dioxide gas to produce an intermediate similar to the gastric ring structure.
2. The obtained intermediate was esterified with n-butyl chloroformate in the presence of potassium carbonate.
3. Finally, the obtained esterified product was hydrolyzed in the presence of sodium bicarbonate to obtain Z-ORN-OH.
As for safety information, Z-ORN-OH are generally considered to be relatively safe. However, it is still a chemical substance that needs to be used and preserved under suitable laboratory conditions. Care should be taken to avoid inhalation, ingestion or contact with skin and eyes. Also, appropriate laboratory practices and the use of personal protective equipment should be followed. During handling and disposal, local regulations and safe operating procedures should be followed. In case of any doubt or uncertainty, it is recommended to seek professional advice.
Last Update:2024-04-09 22:09:11