H2N-PEG4-CH2CH2COOtBu - Names and Identifiers
H2N-PEG4-CH2CH2COOtBu - Physico-chemical Properties
Molecular Formula | C15H31NO6
|
Molar Mass | 321.41 |
Density | 1.040±0.06 g/cm3(Predicted) |
Boling Point | 400.1±35.0 °C(Predicted) |
pKa | 8.74±0.10(Predicted) |
Storage Condition | -20°C |
H2N-PEG4-CH2CH2COOtBu - Upstream Downstream Industry
H2N-PEG4-CH2CH2COOtBu - Introduction
H2N-PEG4-tBu(H2N-PEG4-tBu) is a chemical substance with the following properties, uses, preparation and safety information:
Nature:
H2N-PEG4-tBu is a polyethylene glycol (PEG) Derivative Containing four ethylene glycol (EG) units, one of which is protected by tert-butyl ester. It is a solid powder with good solubility and dispersibility. This compound also has the characteristics of high stability, acid and alkali resistance and temperature.
Use:
H2N-PEG4-tBu are widely used in chemical biology and medicine. Its applications in drug delivery and carrier systems are numerous. This compound can be used as a multifunctional PEGylation reagent for coupling reactions with other compounds. H2N-PEG4-tBu also act as a coating agent that inhibits protein adsorption and cell adhesion.
Method:
A common method of preparing H2N-PEG4-tBu is through a polymerization etherification reaction. First, ethylene glycol (EG) and tert-butoxide (tBu-OH) are subjected to a condensation reaction to obtain a H2N-PEG4-tBu.
Safety Information:
In the use of H2N-PEG4-tBu, should follow the general laboratory safety procedures. The compounds may be irritating to the eyes, skin and mucous membranes. Direct contact with skin and eyes should be avoided. In case of accidental contact, rinse immediately with plenty of water and seek medical help. In addition, H2N-PEG4-tBu should be stored in a dry, cool place, away from fire and oxidizing agents.
Last Update:2024-04-09 21:01:54