L-Ascorbate-2-phosphate
L-Ascorbate-2-phosphate
CAS: 23313-12-4
Molecular Formula: C24H48N3O9P
L-Ascorbate-2-phosphate - Names and Identifiers
L-Ascorbate-2-phosphate - Physico-chemical Properties
| Molecular Formula | C24H48N3O9P |
| Molar Mass | 553.64 |
| Density | 2.01±0.1 g/cm3(Predicted) |
| Boling Point | 682.7±65.0 °C(Predicted) |
| Appearance | White-like or light yellow powder |
| pKa | 1.38±0.10(Predicted) |
| Storage Condition | Room Temprature |
| In vitro study | L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect. L-Ascorbicacid2-phosphate (50 µM-250 µM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 µM AsA2-P and 10 nM dexamethasone (Dex), and 250 µM AsA2-P and 5 nM Dex. Cell Proliferation Assay Cell Line: Humancornealendothelialcells(HCECs) Concentration: 0.1 mM; 0.3 mM; 1.5 mM Incubation Time: 2 to 3 weeks with medium exchange every 2 to 3 days Result: Stimulated HCEC cells growth. |
L-Ascorbate-2-phosphate - Reference
| Reference Show more | 1. [IF=5.833] Zhou Jiao et al."Fluorometric and resonance Rayleigh scattering dual-mode bioprobe for determination of the activity of alkaline phosphatase based on the use of CoOOH nanoflakes and cobalt(II)-dependent DNAzyme-assisted amplification."Microchim Acta. 201 |
L-Ascorbate-2-phosphate - Introduction
L-Ascorbate-2-phosphate, also known as ascorbyl phosphate or ascorbyl -2-phosphate, is a derivative of vitamin C. The following is a description of the nature, use, preparation and safety information of the L-Ascorbate-2-phosphate:
Nature:
1. Appearance: L-Ascorbate-2-phosphate is usually white crystalline powder or crystalline solid.
2. Stability: Compared with vitamin C,L-Ascorbate-2-phosphate has better stability, especially under humid conditions.
3. Solubility: L-Ascorbate-2-phosphate soluble in water and polar solvents.
Use:
1. Antioxidants: L-Ascorbate-2-phosphate has good antioxidant properties and can help protect cells from free radical damage.
2. whitening agent: L-Ascorbate-2-phosphate is widely used in cosmetics and skin care products, can be used to inhibit the formation of melanin, reduce the problem of color spots and uneven skin tone.
3. Fiber Enhancer: L-Ascorbate-2-phosphate can promote the synthesis of collagen, which is beneficial to the growth of skin, hair and nails.
Method:
L-Ascorbate-2-phosphate can be synthesized by reacting vitamin C with a phosphate compound. The specific preparation method will be optimized according to actual needs.
Safety Information:
L-Ascorbate-2-phosphate are generally considered relatively safe and are widely used in cosmetics and skin care products. However, for individuals with strong allergies, the use of L-Ascorbate-2-phosphate may cause allergic reactions. Therefore, it is recommended to perform a skin sensitivity test before use and use it in accordance with the instructions attached to the product. In addition, as a nutritional supplement, excessive intake of L-Ascorbate-2-phosphate can also cause indigestion and other discomfort. Before using any supplement, you should consult your doctor or professional for advice.
Nature:
1. Appearance: L-Ascorbate-2-phosphate is usually white crystalline powder or crystalline solid.
2. Stability: Compared with vitamin C,L-Ascorbate-2-phosphate has better stability, especially under humid conditions.
3. Solubility: L-Ascorbate-2-phosphate soluble in water and polar solvents.
Use:
1. Antioxidants: L-Ascorbate-2-phosphate has good antioxidant properties and can help protect cells from free radical damage.
2. whitening agent: L-Ascorbate-2-phosphate is widely used in cosmetics and skin care products, can be used to inhibit the formation of melanin, reduce the problem of color spots and uneven skin tone.
3. Fiber Enhancer: L-Ascorbate-2-phosphate can promote the synthesis of collagen, which is beneficial to the growth of skin, hair and nails.
Method:
L-Ascorbate-2-phosphate can be synthesized by reacting vitamin C with a phosphate compound. The specific preparation method will be optimized according to actual needs.
Safety Information:
L-Ascorbate-2-phosphate are generally considered relatively safe and are widely used in cosmetics and skin care products. However, for individuals with strong allergies, the use of L-Ascorbate-2-phosphate may cause allergic reactions. Therefore, it is recommended to perform a skin sensitivity test before use and use it in accordance with the instructions attached to the product. In addition, as a nutritional supplement, excessive intake of L-Ascorbate-2-phosphate can also cause indigestion and other discomfort. Before using any supplement, you should consult your doctor or professional for advice.
Last Update：2024-04-09 20:52:54
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