LY-099094
vindesine sulfate
CAS: 59917-39-4
Molecular Formula: C43H57N5O11S
LY-099094 - Names and Identifiers
| Name | vindesine sulfate |
| Synonyms | Fildesi Elsedine LY-099094 vindesine sulfate vindesine sulphate VINCRISITINESULFATE VINDESINE SULFATE SALT Desacetylvinblastine amide sulfate salt |
| CAS | 59917-39-4 |
| EINECS | 261-984-7 |
| InChI | InChI=1/C43H55N5O7.H2O4S/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-47(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)54-4)46(3)35-41(28)15-18-48-16-10-14-40(7-2,34(41)48)36(49)43(35,53)37(44)50;1-5(2,3)4/h8-12,14,19-20,25,34-36,45,49,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H2,44,50);(H2,1,2,3,4)/t25-,34+,35-,36-,39+,40-,41-,42+,43+;/m1./s1 |
LY-099094 - Physico-chemical Properties
| Molecular Formula | C43H57N5O11S |
| Molar Mass | 852 |
| Melting Point | >2500C |
| Solubility | deionized water: ≥50mg/mL |
| Appearance | White-like powder |
| Color | off-white to light yellow |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic |
| MDL | MFCD01675266 |
LY-099094 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 40 - Limited evidence of a carcinogenic effect |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 1544 |
| WGK Germany | 3 |
| RTECS | YY8090000 |
| Hazard Class | 6.1(a) |
| Packing Group | II |
| Toxicity | LD50 in mice, rats (mg/kg): 6.3 ± 0.6, 2.0 ± 0.2 i.v. (Todd); in mice: 8.8 ± 2.5 i.p. (Owellen, Biochem. Pharmacol.) |
LY-099094 - Reference Information
| biological activity | Vindesine sulfate (Eldesine, Eldisine, Desacetyl Vinblastine amide, desacetylblastine amide, DAVA, DVA, VDS) it is a vinca alkaloid extracted from Catharanthus roseus, is a potent inhibitor of mitosis mitosis, and has anti-tumor activity. Vindesine binds to tubulin of the mitotic spindle and can lead to microtubule crystallization and mitotic arrest or cell death. |
| Use | anticancer drug. an inhibitor of tubulin. |
Last Update：2024-04-09 20:52:54
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Mobile: 18021002903
QQ: 3008007409
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