N-(2-Hydroxyethyl)succinimide - Names and Identifiers
N-(2-Hydroxyethyl)succinimide - Physico-chemical Properties
Molecular Formula | C6H9NO3
|
Molar Mass | 143.14 |
Density | 1.3075 (rough estimate) |
Melting Point | 57-61 °C (lit.) |
Boling Point | 160-164 °C/3 mmHg (lit.) |
Flash Point | >230°F |
Solubility | Chloroform (Sparingly) |
Vapor Presure | 2.36E-06mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White Low-Melting |
BRN | 124744 |
pKa | 14.20±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.4290 (estimate) |
MDL | MFCD00078332 |
N-(2-Hydroxyethyl)succinimide - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
|
WGK Germany | 3 |
N-(2-Hydroxyethyl)succinimide - Introduction
N-(2-Hydroxyethyl)succinimide(N-(2-Hydroxyethyl)butyramide) is an organic compound. Its molecular formula is C6H13NO2 and its relative molecular mass is 131.17g/mol.
N-(2-Hydroxyethyl)succinimide is a colorless to pale yellow liquid, soluble in water and some organic solvents.
Its main use is as a substitute reagent for the hydrogen phosphate diester (HOPD) group in organic synthesis, and is used to synthesize organic molecules with pharmaceutical activity. It is also commonly used as a softener, lubricant and preservative.
The preparation of N-(2-Hydroxyethyl)succinimide can be obtained by reacting succinamide with 2-chloroethanol in the presence of sodium hydroxide. The reaction is usually carried out at room temperature.
For safety information, N-(2-Hydroxyethyl)succinimide is irritating to the eyes, skin and respiratory system. Wear protective gloves and goggles during use and ensure adequate ventilation. If ingested or exposed by mistake, seek medical attention immediately and provide information on the chemical.
Last Update:2024-04-09 20:02:46