N-(T-BUTOXYCARBONYL)-1H-PYRAZOLE-1-CARBOXAMIDINE

N-(T-BUTOXYCARBONYL)-1H-PYRAZOLE-1-CARBOXAMIDINE - Names and Identifiers

Name	N-boc-1H-pyrazole-1-carboxamidine
Synonyms	1-(N-Boc-amidino)pyrazole Boc-1H-pyrazole-1-carboxamidine N-boc-1H-pyrazole-1-carboxamidine N-BOC-1H-PYRAZOLE-1-CARBOXAMIDINE N-(T-BUTOXYCARBONYL)-1H-PYRAZOLE-1-CARBOXAMIDINE N-(tert-butoxycarbonyl)-1H-pyrazole-1-carboxamidi tert-butyl [amino(1H-pyrazol-1-yl)methyl]carbamate n-(tert-butoxycarbonyl)-1h-pyrazole-1-carboxamidine tert-Butyl N-(1H-pyrazole-1-carboximidoyl)carbamate N-(tert-Butoxycarbonyl)-1H-pyrazole-1-carboxamidine N-(TERT-BUTOXYCARBONYL)-1 H-PYRAZOLE-1-CARBOXAMIDINE tert-Butyl (amino(1H-pyrazol-1-yl)methylene)carbamate tert-butyl [amino(1H-pyrazol-1-yl)methylidene]carbamate
CAS	152120-61-1
InChI	InChI=1/C9H14N4O2/c1-9(2,3)15-8(14)12-7(10)13-6-4-5-11-13/h4-6H,1-3H3,(H2,10,12,14)
InChIKey	IGSFMHYSWZUENI-UHFFFAOYSA-N

N-(T-BUTOXYCARBONYL)-1H-PYRAZOLE-1-CARBOXAMIDINE - Physico-chemical Properties

Molecular Formula	C9H14N4O2
Molar Mass	210.23
Density	1.21
Melting Point	97-101 °C (lit.)
Boling Point	326.2°C at 760 mmHg
Flash Point	151.1°C
Vapor Presure	0.00022mmHg at 25°C
Appearance	Crystalline powder
BRN	6141956
pKa	9.15±0.46(Predicted)
Storage Condition	2-8°C
Refractive Index	1.558
MDL	MFCD00216663

N-(T-BUTOXYCARBONYL)-1H-PYRAZOLE-1-CARBOXAMIDINE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S60 - This material and its container must be disposed of as hazardous waste. S37 - Wear suitable gloves.
WGK Germany	3
HS Code	29332900

N-(T-BUTOXYCARBONYL)-1H-PYRAZOLE-1-CARBOXAMIDINE - Introduction

N-boc-1H-pyrazole-1-carboxamidine is an organic compound, its chemical name is N-tert-Butoxycarbonyl-1H-pyrazol-1-ylmethanamine. The following is an introduction to its nature, use, preparation and safety information:

1. Nature:
-Appearance: White solid
-Molecular formula: C10H16N2O2
-Molecular weight: 200.25g/mol
-Melting point: about 48-51 degrees Celsius
-Stability: Stable at room temperature, but decomposition may occur when encountering high temperature, light or oxidant

2. Use:
N-boc-1H-pyrazole-1-carboxamidine are commonly used as protecting groups in organic synthesis to protect amino groups. It can be removed by a deprotecting group reaction to give the free 1H-pyrazole-1-carboxamidine.

3. Preparation method:
The preparation method of N-boc-1H-pyrazole-1-carboxamidine is relatively simple, usually through the following steps:
-Reaction of 1H-pyrazole-1-carboxamidine with N-tert-butoxycarbonyl isopropanolamine to generate N-boc-1H-pyrazole-1-carboxamidine.

4. Safety Information:
- N-boc-1H-pyrazole-1-carboxamidine are chemicals and should comply with relevant safety procedures.
-When using or handling, it is necessary to operate in a well-ventilated place to avoid inhaling dust or touching skin.
-Avoid contact with oxidizing agents, strong acids or strong bases to prevent dangerous reactions.
-Storage should be kept sealed, stored in a dry, cool place, away from fire and heat sources.
-If taken by mistake or inhaled, seek medical attention immediately and provide information about the chemical.

The information provided here is for reference only. Please read the relevant chemical safety information and operating instructions carefully before use.

Last Update：2024-04-10 22:29:15