N-BOC-3-BROMOMETHYLPYRROLIDINE - Names and Identifiers
N-BOC-3-BROMOMETHYLPYRROLIDINE - Physico-chemical Properties
Molecular Formula | C10H18BrNO2
|
Molar Mass | 264.16 |
Density | 1.312±0.06 g/cm3(Predicted) |
Boling Point | 300.1±15.0 °C(Predicted) |
pKa | -2.14±0.40(Predicted) |
Storage Condition | 2-8°C |
N-BOC-3-BROMOMETHYLPYRROLIDINE - Risk and Safety
Hazard Symbols | Xn - Harmful
|
Risk Codes | 22 - Harmful if swallowed
|
Hazard Class | IRRITANT |
N-BOC-3-BROMOMETHYLPYRROLIDINE - Introduction
tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate(tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate) is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: It is a colorless to slightly yellow liquid.
-Molecular formula: C10H18BrNO2
-Molecular weight: 259.16g/mol
-Boiling point: 228-230 ° C
-Density: 1.27g/cm³
-Melting point:-12 ° C
Use:
- tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate is widely used as an intermediate in the field of organic synthesis to synthesize various compounds, especially compounds with biological activity.
-can be used to synthesize pesticides, drugs, insecticides, dyes and functional materials.
Method:
- tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate can be synthesized by the following steps:
1. First, pyrrolidine is reacted with methyl bromide.
2. The obtained 3-(bromomethyl) pyrrolidine is reacted with tert-butanoic acid.
3. Finally, the target product is obtained by dehydration reaction.
Safety Information:
- tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate is irritating and corrosive, and care should be taken to avoid contact with skin and eyes.
-Wear suitable personal protective equipment such as goggles, gloves and lab coats when operating.
-During operation, it should be carried out in a well-ventilated environment to avoid inhaling its vapor.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical attention.
Last Update:2024-04-09 21:01:54