t-butyl-3-(bromomethyl)pyrrolidine-1-carboxylate

t-butyl-3-(bromomethyl)pyrrolidine-1-carboxylate - Names and Identifiers

Name	tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate
Synonyms	Boc-3-Bromomethyl-pyrrolidine N-BOC-3-BROMOMETHYLPYRROLIDINE 1-Boc-3-bromomethyl-pyrrolidine 1-N-Boc-3-broMoMethylpyrrolidine 1-Boc-3-(broMoMethyl)pyrrolidine t-butyl-3-(bromomethyl)pyrrolidine-1-carboxylate tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate TERT-BUTYL 3-(BROMOMETHYL)PYRROLIDINE-1-CARBOXYLATE 3-BROMOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS	305329-97-9

t-butyl-3-(bromomethyl)pyrrolidine-1-carboxylate - Physico-chemical Properties

Molecular Formula	C10H18BrNO2
Molar Mass	264.16
Density	1.312±0.06 g/cm3(Predicted)
Boling Point	300.1±15.0 °C(Predicted)
pKa	-2.14±0.40(Predicted)
Storage Condition	2-8°C

t-butyl-3-(bromomethyl)pyrrolidine-1-carboxylate - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed
Hazard Class	IRRITANT

t-butyl-3-(bromomethyl)pyrrolidine-1-carboxylate - Introduction

tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate(tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate) is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: It is a colorless to slightly yellow liquid.
-Molecular formula: C10H18BrNO2
-Molecular weight: 259.16g/mol
-Boiling point: 228-230 ° C
-Density: 1.27g/cm³
-Melting point:-12 ° C

Use:
- tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate is widely used as an intermediate in the field of organic synthesis to synthesize various compounds, especially compounds with biological activity.
-can be used to synthesize pesticides, drugs, insecticides, dyes and functional materials.

Method:
- tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate can be synthesized by the following steps:
1. First, pyrrolidine is reacted with methyl bromide.
2. The obtained 3-(bromomethyl) pyrrolidine is reacted with tert-butanoic acid.
3. Finally, the target product is obtained by dehydration reaction.

Safety Information:
- tert-Butyl 3-(bromomethyl)pyrrolidine-1-carboxylate is irritating and corrosive, and care should be taken to avoid contact with skin and eyes.
-Wear suitable personal protective equipment such as goggles, gloves and lab coats when operating.
-During operation, it should be carried out in a well-ventilated environment to avoid inhaling its vapor.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical attention.

Last Update：2024-04-09 21:01:54