N-Boc-Trans-4-Hydroxy-D-Proline

N-Boc-Trans-4-Hydroxy-D-Proline - Names and Identifiers

Name	(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
Synonyms	BOC-D-HYP-OH Boc-D-trans-Hyp-OH N-Boc-trans-D-Hyp-OH BOC-D-PRO(4-HYDROXY)-OH BOC-TRANS-4-HYDROXY-D-PROLINE N-BOC-CIS-7-HYDROXY-D-PROLINE N-Boc-trans-4-Hydroxy-D-proline (2R,4S)-N-Boc-4-hydroxy-D-proline N-T-BOC-TRANS-4-HYDROXY-D-PROLINE (2R,4S)-N-Boc-cis-4-hydroxy-D-proline (2R,4S)-N-Boc-trans-4-hydroxy-D-proline N-ALPHA-T-BUTOXYCARBONYL-D-HYDROXYPROLINE (4S)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline 1-tert-Butoxycarbonyl-(2R,4S)-4-hydroxypyrrolidine-2-carboxylic acid (2R,4S)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester (2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID
CAS	147266-92-0
EINECS	803-000-6
InChI	InChI=1/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m0/s1

N-Boc-Trans-4-Hydroxy-D-Proline - Physico-chemical Properties

Molecular Formula	C10H17NO5
Molar Mass	231.25
Density	1.312±0.06 g/cm3(Predicted)
Melting Point	123°C
Boling Point	390.9±42.0 °C(Predicted)
Flash Point	190.193°C
Vapor Presure	0mmHg at 25°C
pKa	3.80±0.40(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.531
MDL	MFCD01861341

N-Boc-Trans-4-Hydroxy-D-Proline - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	3
Hazard Class	IRRITANT

N-Boc-Trans-4-Hydroxy-D-Proline - Introduction

(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID is an organic compound with the following characteristics:

Nature:
1. Appearance: white crystalline solid
2. Molecular formula: C11H17NO5
3. Molecular weight: 247.26g/mol
4. Solubility: Soluble in organic solvents, such as dichloromethane, ethanol and methanol
5. Stability: stable at room temperature, but sensitive to light and heat

Use:
(2R,4S)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID is often used as an intermediate in organic synthesis and an important reagent in the research field. It can be used in the synthesis of drugs, bioactive compounds and peptide compounds.

Method:
Preparation of (2R,4S)-Methods for N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID are generally achieved by chemical synthesis. One common method is by reacting trans-4-hydroxy-d-proline with an N-protecting group, such as a Boc Group, to obtain the desired product.

Safety Information:
Use the following safety information:
1. The compound may be irritating, please avoid direct contact with skin, eyes and respiratory tract.
2. In the process of operation, should follow the laboratory safety procedures, wear appropriate protective measures, including laboratory gloves and goggles.
3. Storage should be placed in a dry, cool place, avoid contact with oxygen, moisture and strong acid and other substances.

Last Update：2024-04-09 02:00:42