N-Phthaloylglycine
N-Phthaloylglycine
CAS: 4702-13-0
Molecular Formula: C10H7NO4
N-Phthaloylglycine - Names and Identifiers
| Name | N-Phthaloylglycine |
| Synonyms | Phthaloyl glycine N-Phthaloylglycine Phthalimidoacetic acid 1,3-Dioxo-2-isoindolineacetic acid 1,3-Dihydro-1,3-dioxo-2H-isoindoleacetic acid (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetate (1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid |
| CAS | 4702-13-0 |
| EINECS | 225-177-3 |
| InChI | InChI=1/C10H7NO4/c12-8(13)5-11-9(14)6-3-1-2-4-7(6)10(11)15/h1-4H,5H2,(H,12,13)/p-1 |
N-Phthaloylglycine - Physico-chemical Properties
| Molecular Formula | C10H7NO4 |
| Molar Mass | 205.17 |
| Density | 1.3849 (rough estimate) |
| Melting Point | 195-198℃ |
| Boling Point | 412.6°C at 760 mmHg |
| Flash Point | 203.3°C |
| Water Solubility | insoluble |
| Vapor Presure | 1.51E-07mmHg at 25°C |
| Appearance | White crystal |
| pKa | 3.61±0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| MDL | MFCD00005900 |
| Physical and Chemical Properties | Chemical white odorless crystalline powder. |
| Use | Application of phthaloylglycine as amino acid derivatives, can be used as pharmaceutical intermediates. |
N-Phthaloylglycine - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 3 |
| RTECS | NR3439000 |
| HS Code | 29251900 |
| Hazard Class | IRRITANT |
N-Phthaloylglycine - Upstream Downstream Industry
| Raw Materials | DIPHENYL PHOSPHORAMIDATE Glycine |
| Downstream Products | N-(Bromomethyl)phthalimide |
N-Phthaloylglycine - Introduction
N-Phthaloylglycine(N-Phthaloylglycine) is an organic compound whose chemical formula is C10H7NO4.
The substance is a colorless crystalline solid at room temperature and is soluble in water and some organic solvents. It has two functional groups: one is a phytic acid group (I. e., a phthalic acid group), and the other is a glycine group. This makes the N-Phthaloylglycine in the field of organic synthesis and peptide synthesis has certain application value.
N-Phthaloylglycine are commonly used in substitution reactions and condensation reactions in organic synthesis, and can be used as precursors for ligands or catalysts. In addition, it can also be used as a complexing agent for metal ions, which can form stable complexes with metal ions, and has certain application in coordination chemistry.
There are two main methods for preparing N-Phthaloylglycine: one is obtained by the hydrolysis reaction of phthaloyl glycinate, and the other is obtained by the condensation reaction of phthalic anhydride and glycine.
Regarding safety information, N-Phthaloylglycine has not been identified as a toxic substance, but as a chemical substance, it still needs to be handled with caution. During use, you need to follow the standard operating procedures of the chemical laboratory, wear protective equipment correctly, and avoid contact with skin and eyes. If ingestion or contact occurs, seek medical help immediately.
The substance is a colorless crystalline solid at room temperature and is soluble in water and some organic solvents. It has two functional groups: one is a phytic acid group (I. e., a phthalic acid group), and the other is a glycine group. This makes the N-Phthaloylglycine in the field of organic synthesis and peptide synthesis has certain application value.
N-Phthaloylglycine are commonly used in substitution reactions and condensation reactions in organic synthesis, and can be used as precursors for ligands or catalysts. In addition, it can also be used as a complexing agent for metal ions, which can form stable complexes with metal ions, and has certain application in coordination chemistry.
There are two main methods for preparing N-Phthaloylglycine: one is obtained by the hydrolysis reaction of phthaloyl glycinate, and the other is obtained by the condensation reaction of phthalic anhydride and glycine.
Regarding safety information, N-Phthaloylglycine has not been identified as a toxic substance, but as a chemical substance, it still needs to be handled with caution. During use, you need to follow the standard operating procedures of the chemical laboratory, wear protective equipment correctly, and avoid contact with skin and eyes. If ingestion or contact occurs, seek medical help immediately.
Last Update：2024-04-10 22:29:15
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CAS: 4702-13-0
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Raw Materials for N-Phthaloylglycine
Downstream Products for N-Phthaloylglycine