Polylysine
Polylysine
CAS: 25104-18-1
Molecular Formula: C6H14N2O2
Polylysine - Names and Identifiers
Polylysine - Physico-chemical Properties
| Molecular Formula | C6H14N2O2 |
| Molar Mass | 146.19 |
| Density | 1.125g/cm3 |
| Boling Point | 311.5°Cat760mmHg |
| Flash Point | 142.2°C |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Physical and Chemical Properties | Physicochemical properties ε-polylysine is light yellow powder, strong hygroscopicity and slightly bitter taste. It is a linear polymer of lysine. It was first discovered by Japanese scholars S.Shima and H.Sakai during microbial screening in 1977. It is produced by Streptomyces fermentation and has broad-spectrum antibacterial effect. ε-polylysine is polymerized by 25-30 lysine groups, which is stable to ph and heat. Its antibacterial effect is related to polymerization degree and environment, and its molecular weight is between 3600-4300. At the same time, its hydrolysate is essential lysine, so ε-polylysine is called a nutritional bacteriostatic agent. ε-polylysine has been used in food preservation since the 1980s, but it has not been used for a long time in China. Only in 2014 did the former Health Planning Commission approve ε-polylysine as a new variety of food additives. As a natural preservative, ε-polylysine has unique application conditions. Similar to the benchmark nisin of natural preservatives, it belongs to polypeptide preservatives, and ε-polylysine has a wider antibacterial range than nisin. Most natural preservatives have a good antibacterial effect on Gram-positive bacteria, but have no obvious effect on Gram-negative bacteria such as Escherichia coli, while the appearance of ε-polylysine breaks this "hidden rule". It also has obvious antibacterial and killing effects on Gram-negative bacteria such as Escherichia coli and Arthrobacter products, and has outstanding broad-spectrum antibacterial effects. |
| Use | Synthetic goods are generally sold with 50% effective distribution. For example: alcohol preparation: dextrin powder with mass fraction of 50% Polylysine is used as the basic raw material, and alcohol preparation with volume fraction of 30% ~ 70% is added, which is mainly used for various egg products. Acetic acid preparation: add volume fraction of 5.0% ~ acetic acid, mainly used for rice, salad and other foods; Glycerol preparation: add volume fraction O.01% ~ 5%, mainly used for containing animal protein milk protein more food; Glycine preparation: The amount of mass fraction of 0.01% a 10%, and Poly lysine compound use, synergistic antibacterial effect is better. |
Polylysine - Application field
1. Application in food
At present, & epsilon;-Polylysine is widely used in food and beverages, such as cakes, cakes, fast food, butter, salad dressing, beverages, alcohol, meat products, canned food, etc. For the national standard dosage of different types of food, please refer to the following table.
Food classification number Food name usage
07.0 baked goods 0.15 g/kg
08.03 cooked meat products 0.25 g/kg
14.02 fruit and vegetable juice 0.20g/l
In addition, & epsilon;-polylysine can also be used as a better cleaning fungicide for food machinery and containers in food processing enterprises
2. Application in cosmetics and daily chemical products
Cosmetics are highly susceptible to microbial contamination and corruption in the process of production, storage and use. Cosmetics are deteriorated and moldy due to microbial contamination, which is very harmful to human skin. & epsilon;-Polylysine has broad-spectrum antibacterial properties, which can effectively inhibit the growth of various microorganisms and ensure product quality. & epsilon;-Polylysine is an amino acid polymer, which is a nutritional preservative, so it is more green, environmentally friendly, safe and efficient. In addition, & epsilon;-Polylysine is also widely used in daily chemical products such as toothpaste, mouthwash, soap, hand sanitizer, wet wipes, kitchen cleaning agents, sanitary napkins for women, baby diapers, etc.
3. Application in medicine
& epsilon;-Polylysine is rich in cations, produces strong electrostatic force with anionic substances, and has good penetrating power to biofilms. Based on this characteristic & epsilon;-Polylysine can be used as a carrier for some drugs, so it is widely used in medical pharmacy. & epsilon;-Polylysine and aminometapine (drugs for the treatment of leukemia and tumors) polymerize to improve the efficacy of drugs. To study the damage degree of electric pulse to the cell membrane modified by polylysine with different molecular weight, it is found that the cell membrane adsorption of high molecular weight polylysine will reduce its critical voltage of damage.
Last Update：2024-04-09 21:04:16
Polylysine - Application
Polylysine is a natural biological metabolic product with good bactericidal ability, thermal stability and excellent anti-corrosion performance. It is now widely used in the preservation and preservation of instant rice, wet cooked noodles, cooked vegetables, seafood, sauces, soy sauce, fish fillets and biscuits.
Last Update：2024-04-09 20:52:54
Polylysine - Product characteristics
& epsilon;-polylysine (& epsilon;-poly-L-lysine, abbreviated as & epsilon;-PL) is a homo-monomer polymer containing 25-35 L-lysine residues produced by streptomyces albicans (Streptomyces albulus) through liquid submerged aerobic fermentation. It has obvious inhibitory effects on gram-positive and negative bacteria, yeast, mold, virus, etc, widely used in food, daily chemical, medicine and other industries. The substance can be completely digested and absorbed by the human body and decomposed into lysine necessary for the human body without any toxic side effects.
1. Broad antibacterial spectrum: It can effectively inhibit Gram-positive and negative bacteria, yeast, mold, virus and other microorganisms.
2. High temperature resistance: it does not decompose in high temperature environment (121 ℃,30 minutes), so it can participate in the heat treatment process of products and process and produce together with raw materials.
3. Strong water solubility: & epsilon;-Polylysine is easily soluble in water with a maximum solubility of at least 500g/L.
4. Wide application range of pH: under the condition of pH 2~9, & epsilon;-Polylysine has strong bactericidal ability, which can make up for the low activity of other preservatives under neutral and alkaline conditions.
5. Strong synergy: & epsilon;-As a new type of food preservative and fungicide, polylysine has a good killing effect when used alone, and is more synergistic with other food additives (such as vinegar, ethanol, glycine, organic acid, etc.), which greatly improves the killing effect.
6. High safety: The LD50 of polylysine acute toxicology test is 5 g/kg, which is equivalent to salt. After the human body ingests polylysine, it can be degraded into lysine nutrients, which are absorbed and utilized without any toxic side effects.
7. Both health care functions: Studies have shown that & epsilon;-Polylysine can effectively inhibit enzyme activity and fat absorption, thus reducing the occurrence of obesity.
Last Update：2024-04-09 18:58:34
Polylysine - Reference Information
| product characteristics | ε-poly-L-lysine (ε-PL for short) is a kind of homo-monomer polymer containing 25-35 L-lysine residues produced by streptomyces albicans (Streptomyces albulus) through liquid submerged aerobic fermentation. it has obvious inhibitory effect on gram-positive and negative bacteria, yeast, mold, virus, etc, widely used in food, daily chemical, medicine and other industries. The substance can be completely digested and absorbed by the human body and decomposed into lysine necessary for the human body without any toxic side effects. 1. Broad antibacterial spectrum: It can effectively inhibit Gram-positive and negative bacteria, yeast, mold, virus and other microorganisms. 2. High temperature resistance: it does not decompose in high temperature environment (121 ℃,30 minutes), so it can participate in the heat treatment process of products and process and produce together with raw materials. 3. Strong water solubility: ε-polylysine is easily soluble in water with a maximum solubility of at least 500g/L. 4. pH is widely used: under the condition of pH 2~9, ε-polylysine has strong bactericidal ability, which can make up for the low activity of other preservatives under neutral and alkaline conditions. 5. Strong synergy: ε-polylysine, as a new type of food preservative, has a good killing effect when used alone, and is more synergistic with other food additives (such as vinegar, ethanol, glycine, organic acid, etc.). Greatly improve the killing effect. 6. High safety: the LD50 of polylysine acute toxicology test is 5g/kg, which is equivalent to salt. After the human body ingests polylysine, it can be degraded into lysine nutrients, which are absorbed and utilized without any toxic side effects. 7. Health care function: Studies have shown that ε-polylysine can effectively inhibit enzyme activity and fat absorption, thereby reducing the occurrence of obesity. |
| application field | 1. application in food at present, ε-polylysine is widely used in food and beverage, such as cake, cake, fast food, butter, salad sauce, beverage, wine, meat products, canned food, etc. For the national standard dosage of different types of food, please refer to the following table. Food Classification Number Food Name Usage 07.0 Baked Food 0.15g/kg08.03 Cooked Meat Products 0.25g/kg14.02 Fruit and Vegetable Juice 0.20g/l In addition, ε-polylysine can also be used as a better cleaning fungicide for food machinery and containers in food processing enterprises 2. Application in cosmetics and daily chemical products During the production, storage and use of cosmetics, they are extremely susceptible to microbial contamination and lead to corruption. Cosmetics are deteriorated and moldy due to microbial contamination, which is very harmful to human skin. ε-polylysine has broad-spectrum antibacterial properties, which can effectively inhibit the growth of various microorganisms and ensure product quality. ε-polylysine is an amino acid polymer, which is a nutritional preservative, so it is more environmentally friendly, safe and efficient. In addition, ε-polylysine is also widely used in daily chemical products such as toothpaste, mouthwash, soap, hand sanitizer, wet wipes, kitchen cleaning agents, sanitary napkins for women, baby diapers, etc. 3. Application in medicine ε-polylysine is rich in cations, produces strong electrostatic force with anionic substances, and has good penetration force on biofilms. Based on this characteristic ε-polylysine can be used as a carrier for some drugs, so it is widely used in medical pharmacy. The polymerization of ε-polylysine and aminopurine (a drug for the treatment of leukemia and tumors) can improve the efficacy of the drug. To study the damage degree of the cell membrane modified by different molecular weight polylysine by electric pulse, it is found that the cell membrane adsorption of high molecular weight polylysine will reduce the critical voltage of damage. |
| application | polylysine is a natural biological metabolic product with good sterilization ability, thermal stability and excellent corrosion resistance. It is now widely used in the preservation and preservation of instant rice, wet cooked noodles, cooked vegetables, seafood, sauces, soy sauce, fish fillets and biscuits. |
Last Update：2024-04-10 22:43:14
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Product Name: Lysine Impurity 25 Visit Supplier Webpage Request for quotationCAS: 25104-18-1
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Polylysine Request for quotation
CAS: 25104-18-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 25104-18-1
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
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