Name | paroxetine |
Synonyms | paroxetine PAROXETIENE BASE Paroxetine-002-SR Paroxetine-002-3S4R Paroxetine HCl anhydrous API 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine 3α-(1,3-Benzodioxole-5-yloxymethyl)-4β-(4-fluorophenyl)piperidine 3α-[(1,3-Benzodioxol-5-yl)oxymethyl]-4β-(4-fluorophenyl)piperidine (4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-,(3s,4r)-piperidin (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)Methyl]-4-(4-fluorophenyl)piperidine (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (3S,4R)-1-Methyl-3-[(3,4-(methylene-dioxy)phenoxy)METHYL]-4-(4-fluorophenyl) piperidine |
CAS | 61869-08-7 |
EINECS | 682-717-4 |
InChI | InChI=1/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14?,17-/m0/s1 |
Molecular Formula | C19H20FNO3 |
Molar Mass | 329.37 |
Density | 1.1844 (estimate) |
Melting Point | 114-116°C |
Boling Point | 451.7±45.0 °C(Predicted) |
Flash Point | 227°C |
Vapor Presure | 2.39E-08mmHg at 25°C |
pKa | pKa 9.51 (Uncertain) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.561 |
Physical and Chemical Properties | Paroxetine hydrochloride: C19H20FNO3? HCI. Tiny Flake Crystal, melting point 118 ℃. Paroxetine Hydrochloride Hemihydrate: C19H20FN03? HCI? 1/2H2O. Crystallization, melting point 129~131 deg C. Paroxetine Maleate: C19H20FNO3? C4H4O4. Crystallized from ethanol-diethyl ether, melting point 136-138 °c. [Α] D-87 °(C = 5, ethanol). Acute toxicity LD50 mice (mg/kg):845 subcutaneous injection, 500 oral. |
Use | Used as an antidepressant |
UN IDs | 3249 |
Hazard Class | 6.1(b) |
Packing Group | III |