BRL29060 MedChemExpress (MCE)

Product Name	paroxetine
Synonyms	paroxetine PAROXETIENE BASE Paroxetine-002-SR Paroxetine-002-3S4R Paroxetine HCl anhydrous API 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine 3α-(1,3-Benzodioxole-5-yloxymethyl)-4β-(4-fluorophenyl)piperidine Synonyms paroxetine PAROXETIENE BASE Paroxetine-002-SR Paroxetine-002-3S4R Paroxetine HCl anhydrous API 3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine 3α-(1,3-Benzodioxole-5-yloxymethyl)-4β-(4-fluorophenyl)piperidine 3α-[(1,3-Benzodioxol-5-yl)oxymethyl]-4β-(4-fluorophenyl)piperidine (4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-,(3s,4r)-piperidin (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)Methyl]-4-(4-fluorophenyl)piperidine (3S,4R)-3-((benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine (3S,4R)-1-Methyl-3-[(3,4-(methylene-dioxy)phenoxy)METHYL]-4-(4-fluorophenyl) piperidine
CAS	61869-08-7
EINECS	682-717-4
Chemical Formula	C19H20FNO3
Molecular Weight	329.37
inchi	InChI=1/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14?,17-/m0/s1
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg;500 mg
Price	Email to quote
Descriptions	Paroxetine Paroxetine MedChemExpress (MCE) HY-122272 61869-08-7 BRL29060 99.92% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Paroxetine Paroxetine MedChemExpress (MCE) HY-122272 61869-08-7 BRL29060 99.92% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches. Paroxetine (10-30 μM, 72 h) reduces the viability of MCF-7 cells in a time- and dose-dependent manner[1]. Paroxetine (10-30 μM, 1-12 h) induces mitochondrial-mediated apoptosis in MCF-7, increasing ROS generation[1]. Paroxetine (10 mg/kg, intraperitoneally, once a day for 14 days) reduces neurogenic pain in rats both before and after sciatic nerve injury[2]. Paroxetine (0.3-10 mg/kg, orally, single dose) has anti-anxiety and antidepressant effects in rats, increasing social interaction time[3]. \| \| \| \| \| \| \| \| \| \| [1]. Young-Woo Cho, et al. Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca2+-and p38 MAP Kinase-Dependent ROS Generation. Cancers (Basel). 2019 Jan 9 11(1):64. [Content Brief] [2]. Malek Zarei, et al. Paroxetine attenuates the development and existing pain in a rat model of neurophatic pain. Iran Biomed J. 2014 18(2):94-100. [Content Brief] [3]. S Lightowler, et al. Anxiolytic-like effect of paroxetine in a rat social interaction test. Pharmacol Biochem Behav. 1994 Oct 49(2):281-5. [Content Brief] [4]. M Bourin, et al. Paroxetine: a review. CNS Drug Rev. Spring 2001 7(1):25-47 [Content Brief]
Last Update	2025-04-01 14:45:47

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