二氢小檗碱
dihydroberberine
CAS: 483-15-8
Molecular Formula: C20H19NO4
二氢小檗碱 - Names and Identifiers
| Name | dihydroberberine |
| Synonyms | Nsc331264 Dihydroberbine dihydroberberine 9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydrob 9,10-Dimethoxy-2,3-(methylenedioxy)-13,13a-didehydroberbine 5,8-Dihydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine 6H-1,3-benzodioxolo[5,6-a]benzo[g]quinolizine, 5,8-dihydro-9,10-dimethoxy- 9,10-Dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline 9,10-DiMethoxy-6,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline |
| CAS | 483-15-8 |
| InChI | InChI=1/C20H19NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-9H,5-6,10-11H2,1-2H3 |
二氢小檗碱 - Physico-chemical Properties
| Molecular Formula | C20H19NO4 |
| Molar Mass | 337.37 |
| Density | 1.37±0.1 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 223-224℃ (dec.) |
| Boling Point | 557.8±50.0 °C(Predicted) |
| Flash Point | 170.7°C |
| Vapor Presure | 1.77E-12mmHg at 25°C |
| Appearance | Yellow needle crystal |
| pKa | 3.08±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.678 |
| MDL | MFCD00022312 |
| Physical and Chemical Properties | Yellow crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Berberis. |
二氢小檗碱 - Reference
| Reference Show more | 1. Wang, Kun, et al. "Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry." Journal of pharmaceutical and biomedical analysis 139 (2017): 73-86.https://doi.org/10.1016/ 2. [IF=3.935] Kun Wang et al."Metabolites identification of berberine in rats using ultra-high performance liquid chromatography/quadrupole time-of-flight mass spectrometry."J Pharmaceut Biomed. 2017 May;139:73 |
二氢小檗碱 - Introduction
Dihydroberine is a naturally occurring alkaloid with the chemical name 2,3, 4,5-tetrahydroxyphenyl [1,3]dihydroberberine. It is a yellow crystalline powder, insoluble in water, soluble in organic solvents such as ethanol, acetone and chloroform. Didroberine is stable under alkaline conditions, but it is easily decomposed by light irradiation and oxygen.
dihydroberberine has many pharmacological activities, such as antibacterial, anti-inflammatory and antioxidant. Therefore, it has a wide range of applications in the field of medicine. It can be used to treat infectious and inflammatory diseases, such as bacterial infections, digestive system diseases and skin inflammation. In addition, dihydroberberine can also be used as an ingredient in cosmetics and sunscreens.
The preparation method of dihydroberberine can generally be obtained by extracting natural plant Phellodendron. Phellodendron chinensis is rich in dihydroberberine, which can be separated and purified by alcohol extraction and extraction.
You need to pay attention to its safety when using or contacting dihydroberberine. dihydroberberine has a certain toxicity, should avoid direct contact and inhalation. At the same time, contact with strong acids and strong oxidants should be avoided to avoid dangerous reactions. In use, follow safe operating procedures and wear appropriate personal protective equipment. In the case of accidental contact or accidental ingestion, you should seek immediate help from your doctor.
dihydroberberine has many pharmacological activities, such as antibacterial, anti-inflammatory and antioxidant. Therefore, it has a wide range of applications in the field of medicine. It can be used to treat infectious and inflammatory diseases, such as bacterial infections, digestive system diseases and skin inflammation. In addition, dihydroberberine can also be used as an ingredient in cosmetics and sunscreens.
The preparation method of dihydroberberine can generally be obtained by extracting natural plant Phellodendron. Phellodendron chinensis is rich in dihydroberberine, which can be separated and purified by alcohol extraction and extraction.
You need to pay attention to its safety when using or contacting dihydroberberine. dihydroberberine has a certain toxicity, should avoid direct contact and inhalation. At the same time, contact with strong acids and strong oxidants should be avoided to avoid dangerous reactions. In use, follow safe operating procedures and wear appropriate personal protective equipment. In the case of accidental contact or accidental ingestion, you should seek immediate help from your doctor.
Last Update：2024-04-09 19:05:02
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