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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameML267 TFA salt
SynonymsML267;ML267 TFA;ML267 TFA salt;4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate
CAS1542213-67-1
EINECS
Chemical FormulaC19H18ClF6N5O3S
Molecular Weight545.89
inchi
Package1 mg
PriceEmail to quote
DescriptionsML267

ML267

MedChemExpress (MCE)

HY-137502

1542213-67-1

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US

Descriptions

ML267

ML267

MedChemExpress (MCE)

HY-137502

1542213-67-1

Please store the product under the recommended conditions in the Certificate of Analysis.

Room temperature in continental US
may vary elsewhere.

ML267 a potent Sfp phosphopantetheinyl transferase (PPTases) inhibitor with an IC50 of 0.29 μM. ML267 also inhibits AcpS-PPTase with an IC50 of 8.1 μM. ML267 possesses specific Gram-positive-targeted bactericidal activities.

IC50: 0.29 μM (Sfp-PPTases) and 8.1 μM (AcpS-PPTase)[1] Molecular Weight 545.89

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[1]. Foley TL, et al. J. 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth. J Med Chem. 2014 Feb 13
57(3):1063-78. [Content Brief]

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