GW542573X MedChemExpress (MCE)

Product Name	GW 542573X
Synonyms	GW 542573X 4-(2-Methoxy-phenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester 4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester Synonyms GW 542573X 4-(2-Methoxy-phenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester 4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester 1-Piperidinecarboxylic acid, 4-[[[[(2-Methoxyphenyl)aMino]carbonyl]oxy]Methyl]-, 1,1-diMethylethyl ester
CAS	660846-41-3
EINECS
Chemical Formula	C19H28N2O5
Molecular Weight	364.44
inchi
Package	1 mg;5 mg;10 mg;25 mg
Price	Email to quote
Descriptions	GW542573X GW542573X MedChemExpress (MCE) HY-12550 660846-41-3 98.79% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions GW542573X GW542573X MedChemExpress (MCE) HY-12550 660846-41-3 98.79% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. GW542573X is a potent and selective Ca2+-activated K+ 2 (SK2) channels activator. GW542573X induces the Ca2+-response curve of hSK1 that left-shifted from an EC50 (Ca2+) value of 410 nM to 240 nM. \| \| \| \| \| \| \| \| \| \| [1]. Hougaard C, et, al. Selective activation of the SK1 subtype of human small-conductance Ca2+-activated K+ channels by 4-(2-methoxyphenylcarbamoyloxymethyl)-piperidine-1-carboxylic acid tert-butyl ester (GW542573X) is dependent on serine 293 in the S5 segment. Mol Pharmacol. 2009 Sep 76(3):569-78. [Content Brief]
Last Update	2025-04-01 14:45:47

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