Dehydrodiacetovanillone MedChemExpress (MCE)

Product Name	Diapocynin
Synonyms	Diapocynin
CAS	29799-22-2
EINECS
Chemical Formula	C18H18O6
Molecular Weight	330.33
inchi
Package	1 mg
Price	Email to quote
Descriptions	Diapocynin Diapocynin MedChemExpress (MCE) HY-121097 29799-22-2 Dehydrodiacetovanillone Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US Descriptions Diapocynin Diapocynin MedChemExpress (MCE) HY-121097 29799-22-2 Dehydrodiacetovanillone Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Diapocynin (Dehydrodiacetovanillone), a dimeric derivative of Apocynin, is an orally active NADPH oxidase inhibitor. Diapocynin has anti-inflammatory, neuroprotection and antioxidant activities. Diapocynin (300 mg/kg p.o. every 12 hours for 72 hours) significantly rescues DFP-induced motor impairment, attenuates epileptiform spiking during the first 72h post-DFP. Diapocynin significantly reduces DFP-induced reactive astrogliosis, neurodegeneration, GP91phox, glutathiolated protein, serum nitrite, or pro-inflammatory cytokines and chemokines such as interleukins (IL) IL-1α, IL-6, IL-2, IL-17A, Leptin, IP-10 in the hippocampus[1]. \| \| \| \| \| \| \| \| \| \| [1]. Marson Putra, et al. Diapocynin, an NADPH oxidase inhibitor, counteracts diisopropylfluorophosphate-induced long-term neurotoxicity in the rat model. Ann N Y Acad Sci. 2020 Nov 1479(1):75-93. [Content Brief]
Last Update	2025-04-01 14:45:47

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