Pronetupitant chloride monohydrochloride MedChemExpress (MCE)

Product Name	Fosnetupitant chloride hydrochloride
Synonyms	Fosnetupitant chloride hydrochloride
CAS	1643757-72-5
EINECS
Chemical Formula	C31H36F6N4O5P. HCl. Cl
Molecular Weight	761.52
inchi
Package	10 mM * 1 mL;1 mg
Price	Email to quote
Descriptions	Fosnetupitant chloride monohydrochloride Fosnetupitant chloride monohydrochloride MedChemExpress (MCE) HY-133206A 1643757-72-5 Pronetupitant chloride monohydrochloride 99.70% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Fosnetupitant chloride monohydrochloride Fosnetupitant chloride monohydrochloride MedChemExpress (MCE) HY-133206A 1643757-72-5 Pronetupitant chloride monohydrochloride 99.70% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Fosnetupitant chloride monohydrochloride (Pronetupitant chloride monohydrochloride) is an NK1 antagonist with pKi values of 9.5, 6.1 for human NK1 and NK3 receptor, respectively. Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of Netupitant. Fosnetupitant chloride monohydrochloride displays a micromolar affinity for the 5-HT6 (pKi ∼ 5.2) receptor and type L Ca2+ channels (pKi ∼ 5.7) and does not bind all the other proteins investigated[1]. Fosnetupitant chloride monohydrochloride (i.v.) is converted in few minutes to Netupitant (HY-16346) invivo[1]. hNK1 9.5 (pKi) hNK3 6.1 (pKi) \| \| \| \| \| \| \| \| \| \| [1]. Ruzza C, et al. In vitro and in vivo pharmacological characterization of Pronetupitant, a prodrug of the neurokinin 1 receptor antagonist Netupitant. Peptides. 2015 Jul 69:26-32. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-04-01 14:45:47

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-04-01 14:45:47

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-04-01 14:45:47

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-04-01 14:45:47

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-04-01 14:45:47

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-04-01 14:45:47

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-04-01 14:45:47

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact