PEG2000PEG2000
MedChemExpress (MCE)
HY-Y0873B
25322-68-3
Polyethylene glycol 2000
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture)
Room temperature in continental US
may vary elsewhere.
PEG2000 (Polyethylene glycol 2000) is a solvent for a large number of substances. PEG2000 can be used as a carrier material and modifying agent. PEG2000 is widely used in a variety of pharmaceutical formulations.
The FDA has approved polyethylene glycol (PEG) for use as a vehicle or base in foods, cosmetics and pharmaceuticals, including injectable, topical, rectal and nasal formulations. PEG shows little toxicity, and is eliminated from the body intact by either the kidneys (for PEGs 20 kDa). PEG lacks immunogenicity, and antibodies to PEG are generated in rabbits only if PEG is combined with highly immunogenic proteins[2].
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[1]. Hong Y, et al. Effect of PEG2000 on drug delivery characterization from solid lipid nanoparticles. Pharmazie. 2006 Apr
61(4):312-5. [Content Brief]
[2]. Harris JM, et al. Effect of pegylation on pharmaceuticals. Nat Rev Drug Discov. 2003 Mar
2(3):214-21. [Content Brief]