GS 4104 MedChemExpress (MCE)

Product Name	Oseltamivir
Synonyms	TAMIFLU GS 4104 GOP-A-Flu Oseltamivr OSELTAMIVIR Oseltamivir OSTELTAMIVIR Synonyms TAMIFLU GS 4104 GOP-A-Flu Oseltamivr OSELTAMIVIR Oseltamivir OSTELTAMIVIR Oseltamivir (free base) (3R,5S)-ethyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate ethyl (3R,4R,5S)-5-aMino-4-acetaMido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate ethyl (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
CAS	196618-13-0
EINECS	1308068-626-2
Chemical Formula	C16H28N2O4
Molecular Weight	312.4
inchi	InChI=1/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1
Package	10 mM * 1 mL;5 mg;10 mg
Price	Email to quote
Descriptions	Oseltamivir Oseltamivir MedChemExpress (MCE) HY-13317 196618-13-0 GS 4104 99.94% 4°C, protect from light In solvent : -80°C, 6 months Descriptions Oseltamivir Oseltamivir MedChemExpress (MCE) HY-13317 196618-13-0 GS 4104 99.94% 4°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively. Oseltamivir (20 mg/kg/day, p.o., twice daily for 10 days) prevented death in the H1N1pdm virus infection in mice[2]. Oseltamivir (10 mg/kg/day, oral gavage, 5 days) together with Amantadine (HY-B0402) (15 or 30 mg/kg) has greater protection efficiency against H5N1 influenza virus infection in mice than monotherapy[3]. Oseltamivir is also used together with Ribavirin (HY-B0434), or Favipiravir (HY-14768), or Peramivir (HY-17015A) to prevent influenza virus infection in mice[4][5]. \| \| \| \| \| \| \| \| \| \| [1]. O Ferraris, et al. Sensitivity of Influenza Viruses to Zanamivir and Oseltamivir: A Study Performed on Viruses Circulating in France Prior to the Introduction of Neuraminidase Inhibitors in Clinical Practice. Antiviral Res. 2005 Oct 68(1):43-8. [Content Brief] [2]. Smee DF, et al. Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm and H3N2 virus infections in mice. Antiviral Res. 2016 Dec 136:45-50. [Content Brief] [3]. Ilyushina NA, et al. Amantadine-oseltamivir combination therapy for H5N1 influenza virus infection in mice. Antivir Ther. 2007 12(3):363-70. [Content Brief] [4]. Ilyushina NA, et al. Oseltamivir-ribavirin combination therapy for highly pathogenic H5N1 influenza virus infection in mice. Antimicrob Agents Chemother. 2008 Nov 52(11):3889-97. [Content Brief] [5]. Smee DF, et al. Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice. Antiviral Res. 2010 Oct 88(1):38-44. [Content Brief]
Last Update	2025-04-01 14:45:47

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