AR-13324 hydrochloride MedChemExpress (MCE)

Product Name	Netarsudil (AR-13324) 2HCl
Synonyms	Netarsudil RHOPRESSA NETARSUDIL AR13324 HCl AR-13324 HCl AR13324 HCL AR-13324 HCL Synonyms Netarsudil RHOPRESSA NETARSUDIL AR13324 HCl AR-13324 HCl AR13324 HCL AR-13324 HCL AR-13324 (hydrochloride) Netarsudil hydrochloride NETARSUDIL HYDROCHLORIDE Netarsudil dihydrochloride Netarsudil (AR-13324) 2HCl
CAS	1253952-02-1
EINECS
Chemical Formula	C28H29Cl2N3O3
Molecular Weight	526.45416
inchi
Package	1 mg;2 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Netarsudil hydrochloride Netarsudil hydrochloride MedChemExpress (MCE) HY-12798B 1253952-02-1 AR-13324 hydrochloride 99.77% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Netarsudil hydrochloride Netarsudil hydrochloride MedChemExpress (MCE) HY-12798B 1253952-02-1 AR-13324 hydrochloride 99.77% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Netarsudil hydrochloride (AR-13324 hydrochloride) is a Rho-associated protein kinas (ROCK) and norepinephrine transporter (NET) inhibitor. Netarsudil hydrochloride has effective in intraocular pressure (IOP) reduction. Netarsudil hydrochloride (0.04%, 50 ΜL)reduces intraocular pressure (IOP) in normotensive monkey eyes[1]. Netarsudil hydrochloride (0.04%) produces statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted rabbits[2]. ROCK, NET[1][2] In Vivo Netarsudil hydrochloride (0.04%, 50 ΜL)reduces intraocular pressure (IOP) in normotensive monkey eyes[1]. Netarsudil hydrochloride (0.04%) produces statistically significant lowering of episcleral venous pressure (EVP) in Dutch Belted rabbits[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Adult female cynomolgus monkeys (3-5 kg)[1] \| \| \| \| \| \| \| \| \| \| [1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan 24(1):51-54. [Content Brief] [2]. Kiel JW, et al. Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits. J Ocul Pharmacol Ther. 2015 Apr 31(3):146-151. [Content Brief]
Last Update	2025-04-01 14:45:47

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