Iodoacetic acid sodium salt MedChemExpress (MCE)

Product Name	Iodoacetic acid, sodium salt
Synonyms	SODIUM IODOACETATE Sodium iodoacetate SODIUM MONOIODOACETATE Iodoacetic acid sodium salt IODOACETIC ACID SODIUM SALT Iodoacetic acid, sodium salt SODIUM IODACETATE SODIUM SALT Synonyms SODIUM IODOACETATE Sodium iodoacetate SODIUM MONOIODOACETATE Iodoacetic acid sodium salt IODOACETIC ACID SODIUM SALT Iodoacetic acid, sodium salt SODIUM IODACETATE SODIUM SALT SODIUM IODOACETATE, SIGMAULTRA IODOACETICACIDSODIUMSALT,REAGENT
CAS	305-53-3
EINECS	206-165-7
Chemical Formula	C2H2INaO2
Molecular Weight	207.93
inchi	InChI=1/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
Package	1 g;5 g;10 g;25 g
Price	Email to quote
Descriptions	Sodium iodoacetate Sodium iodoacetate MedChemExpress (MCE) HY-D0849 305-53-3 Iodoacetic acid sodium salt 99.91% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Sodium iodoacetate Sodium iodoacetate MedChemExpress (MCE) HY-D0849 305-53-3 Iodoacetic acid sodium salt 99.91% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Sodium iodoacetate is a specific inhibitor of GAPDH and has glycolysis inhibitory activity. In addition, sodium iodoacetate can induce osteoarthritis and related pain models in experimental animals. Sodium iodoacetate (0, 0.3 and 3 mg/joint injected into the right knee joint space single dose injection) causes proliferation and moderate fibrosis of synovial cells in Wistar rats, accompanied by mild inflammatory cell infiltration[3]. \| \| \| \| \| \| \| \| \| \| [1]. Xu, Y. et al. Glycolysis in Innate Immune Cells Contributes to Autoimmunity. Frontiers in Immunology, 13. [Content Brief] [2]. Na, H. et al. Soluble CCR2 gene therapy controls joint inflammation, cartilage damage, and the progression of osteoarthritis by targeting MCP-1 in a monosodium iodoacetate (MIA)-induced OA rat model. Journal of Translational Medicine, 20(1) [Content Brief] [3]. Kobayashi K, et al. Sodium iodoacetate-induced experimental osteoarthritis and associated pain model in rats[J]. Journal of Veterinary Medical Science, 2003, 65(11): 1195-1199. [Content Brief] [4]. Güler N, et al. Sodium iodoacetate induced osteoarthrosis model in rabbit temporomandibular joint: CT and histological study (part I)[J]. International journal of oral and maxillofacial surgery, 2011, 40(11): 1289-1295. [Content Brief]
Last Update	2025-04-01 14:45:47

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