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| Supplier Name | MedChemExpress (MCE) |
| Contact | sales |
| Tel | 609-228-6898 |
| Mobile | 609-228-6898 |
| sales@medchemexpress.com; tech@medchemexpress.com | |
| Website | https://www.medchemexpress.com/ |
| Product Name | Sorafenib |
| Synonyms | Nexavar NEXAVAR Forafenib Sorafenib BAY43-9006 Sorafenib-d4 Sorafenib base |
| CAS | 284461-73-0 |
| EINECS | 608-209-4 |
| Chemical Formula | C21H16ClF3N4O3 |
| Molecular Weight | 464.82 |
| inchi | InChI=1/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25 1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31) 2-5H,1H3,(H,8,9,10) |
| Package | 5 mg;10 mg;25 mg;50 mg;100 mg |
| Price | Email to quote |
| Descriptions | Sorafenib (Standard) MedChemExpress (MCE) HY-10201R 99.71% Please store the product under the recommended conditions in the Certificate of Analysis. Sorafenib (Standard) is the analytical standard of Sorafenib. This product is intended for research and analytical applications. Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator. |
| Last Update | 2025-04-01 14:45:47 |
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