Bis-eugenol; Dehydrodieugenol MedChemExpress (MCE)

Product Name	DEHYDRODIEUGENOL
Synonyms	DEHYDRODIEUGENOL
CAS	4433-08-3
EINECS
Chemical Formula	C20H22O4
Molecular Weight	326.39
inchi
Package	1 mg;5 mg;10 mg
Price	Email to quote
Descriptions	Dieugenol Dieugenol MedChemExpress (MCE) HY-130743 4433-08-3 Bis-eugenol Descriptions Dieugenol Dieugenol MedChemExpress (MCE) HY-130743 4433-08-3 Bis-eugenol Dehydrodieugenol Please store the product under the recommended conditions in the Certificate of Analysis. Room temperature in continental US may vary elsewhere. Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages. \| \| \| \| \| \| \| \| \| \| [1]. Ogata, et al. Antioxidant activity of eugenol and related monomeric and dimeric compounds. Chem. Pharm. Bull. (Tokyo) 48(10), 1467-1469 (2000).
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Last Update	2025-05-21 16:50:25

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