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Product Name	(-)-CYANOPINDOLOL HEMIFUMARATE
Synonyms	(-)-CYANOPINDOLOL HEMIFUMARATE s(-)-cyanopindolol hemifumarate salt 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile 4-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-1H-indole-2-c arbonitrile Synonyms (-)-CYANOPINDOLOL HEMIFUMARATE s(-)-cyanopindolol hemifumarate salt 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carbonitrile 4-{2-Hydroxy-3-[(2-methyl-2-propanyl)amino]propoxy}-1H-indole-2-c arbonitrile 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]-1h-indole-2-carbonitrile hemifumarate salt
CAS	69906-85-0
EINECS
Chemical Formula	C16H21N3O2
Molecular Weight	287.36
inchi
Package	1 mg;5 mg;10 mg;25 mg
Price	Email to quote
Descriptions	Cyanopindolol Cyanopindolol MedChemExpress (MCE) HY-W795507 69906-85-0 98.67% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions Cyanopindolol Cyanopindolol MedChemExpress (MCE) HY-W795507 69906-85-0 98.67% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. Cyanopindolol is an β3-adrenoceptor antagonist. Cyanopindolol is a potent and selective antagonist at the presynaptic serotonin autoreceptor in the rat brain cortex. Cyanopindolol has binding affinity for 5-HT1A and 5-HT1B receptor (Ki: 2.1 and 3 nM respectively). β3 adrenoceptor 5-HT1A Receptor 2.1 nM (Ki) 5-HT1B Receptor 3 nM (Ki) \| \| \| \| \| \| \| \| \| \| [1]. Hoey A, et al. Atypical responses of rat ileum to pindolol, cyanopindolol and iodocyanopindolol. Br J Pharmacol. 1996 Feb 117(4):712-6. [Content Brief] [2]. Schlicker E, et al. Cyanopindolol is a highly potent and selective antagonist at the presynaptic serotonin autoreceptor in the rat brain cortex. Naunyn Schmiedebergs Arch Pharmacol. 1985 Dec 331(4):398-401. [Content Brief] [3]. Langlois M, et al. Structural analysis by the comparative molecular field analysis method of the affinity of beta-adrenoreceptor blocking agents for 5-HT1A and 5-HT1B receptors. Eur J Pharmacol. 1993 Jan 4 244(1):77-87. [Content Brief]
Last Update	2025-04-01 14:45:47

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