5,6-Dihydroxyindole-2-carboxylic acid MedChemExpress (MCE)

Product Name	5,6-Dihydroxyindole-2-carboxylic Acid
Synonyms	LEVODOPA IMPURITY 4 Dopamine Impurity 8 Levodopa Impurity 13 2-Carboxy-5,6-dihydroxyindole 5,6-Dihydroxy-2-carboxyindole 5,6-Dihydroxyindole-2-carboxylic Acid 5,6-Dihydroxyindole-2-carboxylic acid Synonyms LEVODOPA IMPURITY 4 Dopamine Impurity 8 Levodopa Impurity 13 2-Carboxy-5,6-dihydroxyindole 5,6-Dihydroxy-2-carboxyindole 5,6-Dihydroxyindole-2-carboxylic Acid 5,6-Dihydroxyindole-2-carboxylic acid 5,6-dihydroxy-2-indolylcarboxylic acid 5,6-dihydroxy-1H-indole-2-carboxylic acid 1H-Indole-2-carboxylicacid, 5,6-dihydroxy-
CAS	4790-08-3
EINECS
Chemical Formula	C9H7NO4
Molecular Weight	193.16
inchi
Package	25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	DHICA DHICA MedChemExpress (MCE) HY-W018158 4790-08-3 5,6-Dihydroxyindole-2-carboxylic acid 95.63% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions DHICA DHICA MedChemExpress (MCE) HY-W018158 4790-08-3 5,6-Dihydroxyindole-2-carboxylic acid 95.63% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an intermediate in melanin synthesis and a component of true black pigment, and it’s also a moderately potent GPR35 agonist. DHICA shows an ability to stimulate β-arrestin translocation signaling with an EC50 value of 23.2 μM in the U2OS cell line. DHICA plays a significant role in promoting and protecting against DNA damage. Human Endogenous Metabolite \| \| \| \| \| \| \| \| \| \| [1]. Huayun Deng, et al. Synthesis and Agonistic Activity at the GPR35 of 5,6-Dihydroxyindole-2-carboxylic Acid Analogues. ACS Med Chem Lett. 2012 Jun 6 3(7):550-4. [Content Brief] [2]. Maria Carolina Pellosi, et al. Effects of the melanin precursor 5,6-dihydroxy-indole-2-carboxylic acid (DHICA) on DNA damage and repair in the presence of reactive oxygen species. Arch Biochem Biophys. 2014 Sep 1:557:55-64. [Content Brief]
Supplier Website	https://www.medchemexpress.com/dhica.html
Last Update	2025-05-21 16:50:25

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