(R)-Ibuprofen MedChemExpress (MCE)

Product Name	(R)-(-)-IBUPROFEN
Synonyms	l-Ibuprofen levibuprofen (R)-IBUPROFEN (-)-Ibuprophen (R)-(-)-IBUPROFEN (R)-2-(4-Isobutylphenyl)propanoic acid (R)-(-)-2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID Synonyms l-Ibuprofen levibuprofen (R)-IBUPROFEN (-)-Ibuprophen (R)-(-)-IBUPROFEN (R)-2-(4-Isobutylphenyl)propanoic acid (R)-(-)-2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (R)- Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (αR)-
CAS	51146-57-7
EINECS
Chemical Formula	C13H18O2
Molecular Weight	206.28
inchi
Package	10 mM * 1 mL;200 mg
Price	Email to quote
Descriptions	(R)-(-)-Ibuprofen (R)-(-)-Ibuprofen MedChemExpress (MCE) HY-78131B 51146-57-7 (R)-Ibuprofen 99.96% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions (R)-(-)-Ibuprofen (R)-(-)-Ibuprofen MedChemExpress (MCE) HY-78131B 51146-57-7 (R)-Ibuprofen 99.96% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, inactive on COX, inhibits NF-κB activation (R)-(-)-Ibuprofen exhibits anti-inflammatory and antinociceptive effects. (R)-(-)-Ibuprofen is the R enantiomer of Ibuprofen, with no inhibitory effect on COX, but is involved in pathways of lipid metabolism and is incorporated into triglycerides along with endogenous fatty acids[1]. (R)-(-)-Ibuprofen (1 μM) significantly reduces NF-κB activation and completely prevents NF-κB induction at 10 μM. (R)-(-)-Ibuprofen inhibits NF-κB luciferase activity with an IC50 of 121.8 μM, weaker than that of S(+)-ibuprofen (IC50, 61.7 μM). Furthermore, (R)-(-)-Ibuprofen (10 mM) has no effect on HSF[2]. NF-κB \| \| \| \| \| \| \| \| \| \| [1]. Evans AM, et al. Comparative pharmacology of S(+)-ibuprofen and (RS)-ibuprofen. Clin Rheumatol. 2001 Nov 20 Suppl 1:S9-14. [Content Brief] [2]. Scheuren N, et al. Modulation of transcription factor NF-kappaB by enantiomers of the nonsteroidal drug ibuprofen. Br J Pharmacol. 1998 Feb 123(4):645-52. [Content Brief]
Last Update	2025-04-01 14:45:47

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