Gabapentin MedChemExpress (MCE)

Product Name	Gabapentin
Synonyms	GOE-3450 neurontin NEURONTIN GABAPENTIN AKOS 92109 Gabapentin GABAPENTINE Synonyms GOE-3450 neurontin NEURONTIN GABAPENTIN AKOS 92109 Gabapentin GABAPENTINE GABAPENTIN HYDROCHLORIDE 1-(AMINOMETHYL)CYCLOHEXANEACETIC ACID 1-(aminomethyl)cyclohexaneacetic acid [2-(aminomethyl)cyclohexyl]acetic acid (1-aminomethyl-cyclohexyl)-acetic acid (1-AMINOMETHYL-CYCLOHEXYL)-ACETIC ACID
CAS	60142-96-3
EINECS	262-076-3
Chemical Formula	C9H17NO2
Molecular Weight	171.24
inchi	InChI=1/C9H17NO2/c10-6-8-4-2-1-3-7(8)5-9(11)12/h7-8H,1-6,10H2,(H,11,12)
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	Gabapentin Gabapentin MedChemExpress (MCE) HY-A0057 60142-96-3 98.0% Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Gabapentin Gabapentin MedChemExpress (MCE) HY-A0057 60142-96-3 98.0% Store at room temperature 3 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker. Gabapentin inhibits neuronal Ca2+ influx and reduction of neurotransmitter release. Gabapentin is a GABA analog that can be used to relieve neuropathic pain. Gabapentin (0-300 μM) produces a concentration-dependent inhibition of the K+-induced [Ca2+]i increase in synaptosomes (IC50=14?μM maximal inhibition by 36%)[1].?Gabapentin (100? μM) decreases the K+-evoked release of endogenous aspartate and glutamate in neocortical slices by 16 and 18%, respectively[1].?Gabapentin (0-1000 μM) reduces the K+-evoked [3H]-noradrenaline release in neocortical slices (IC50=48?μM maximal inhibition of 46%) but not from synaptosomes[1]. Gabapentin (5 and 10 mg/kg i.p. once male BALB/c mice) has improving effects on spatial and emotional cognitive performance of naive mice in Morris water maze (MWM), passive avoidance (PA) and modified elevated plus maze (mEPM) tasks[2].?Gabapentin (1-100 mg/kg i.p. once male mice) has analgesic effect and reduces writhing in a dose-dependent manner[3]. \| \| \| \| \| \| \| \| \| \| [1]. Fink K, et, al. Inhibition of neuronal Ca(2+) influx by gabapentin and subsequent reduction of neurotransmitter release from rat neocortical slices. Br J Pharmacol. 2000 Jun 130(4):900-6. [Content Brief] [2]. Celikyurt IK, et, al. Gabapentin, A GABA analogue, enhances cognitive performance in mice. Neurosci Lett. 2011 Apr 1 492(2):124-8. [Content Brief] [3]. Meymandi MS, et, al. Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur J Anaesthesiol. 2008 Feb 25(2):129-34. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-04-01 14:45:47

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-04-01 14:45:47

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-04-01 14:45:47

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-04-01 14:45:47

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-04-01 14:45:47

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-04-01 14:45:47

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-04-01 14:45:47

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact