DB07268 MedChemExpress (MCE)

Product Name	DB07268
Synonyms	CS-2303 DB07268 DB 07268 DB-07268 DB07268 (DB 07268 2-(4-(3-hydroxyphenylamino)pyrimidin-2-ylamino)benzamide 2-[[2-[(3-Hydroxyphenyl)amino]-4-pyrimidinyl]amino]benzamide Synonyms CS-2303 DB07268 DB 07268 DB-07268 DB07268 (DB 07268 2-(4-(3-hydroxyphenylamino)pyrimidin-2-ylamino)benzamide 2-[[2-[(3-Hydroxyphenyl)amino]-4-pyrimidinyl]amino]benzamide Benzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]-
CAS	929007-72-7
EINECS
Chemical Formula	C17H15N5O2
Molecular Weight	321.33
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg
Price	Email to quote
Descriptions	DB07268 DB07268 MedChemExpress (MCE) HY-15737 929007-72-7 99.92% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions DB07268 DB07268 MedChemExpress (MCE) HY-15737 929007-72-7 99.92% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. DB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively[1]. JNK1 9 nM (IC50) CHK1 0.82 μM (IC50) PAK4 5.5 μM (IC50) AKT1 15 μM (IC50) ERK2 25 μM (IC50) \| \| \| \| \| \| \| \| \| \| [1]. Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1 17(3):668-72. [Content Brief]
Last Update	2025-04-01 14:45:47

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