CID 2011756 MedChemExpress (MCE)

Product Name	5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide
Synonyms	CID2011756 CID-2011756 CID 2011756 CID-2011756 5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide 5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide Synonyms CID2011756 CID-2011756 CID 2011756 CID-2011756 5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide 5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide 5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide
CAS	638156-11-3
EINECS	804-083-1
Chemical Formula	C22H21ClN2O3
Molecular Weight	396.87
inchi
Package	10 mM * 1 mL;5 mg;10 mg;25 mg;50 mg;100 mg
Price	Email to quote
Descriptions	CID 2011756 CID 2011756 MedChemExpress (MCE) HY-13454 638156-11-3 96.98% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions CID 2011756 CID 2011756 MedChemExpress (MCE) HY-13454 638156-11-3 96.98% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 μM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 μM, respectively). CID 2011756 also has antitumor activity. CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50 of 3.2 μM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916 in LNCaP cancer cells with an EC50 of 10±0.7 μM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 μM and 0.7±0.2 μM for PKD2 and PKD3, respectively[1]. Cellular PKD2 0.6 μM (IC50) Cellular PKD3 0.7 μM (IC50) PKD1 3.2 μM (IC50) \| \| \| \| \| \| \| \| \| \| [1]. Sharlow ER, et al. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One. 2011 6(10):e25134. [Content Brief]
Last Update	2025-04-01 14:45:47

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