ONC201 isomer MedChemExpress (MCE)

Product Name	TIC10
Synonyms	TIC10 TIC-10 TIC 10 CS-826 TIC10 TIC 10 NSC 350625 Synonyms TIC10 TIC-10 TIC 10 CS-826 TIC10 TIC 10 NSC 350625 ONC201 ISOMER 7-benzyl-10-(2-Methylbenzyl)-2,6,7,8,9,10-hexahydroiMidazo[1,2-a]pyrido[4,3-d]pyriMidin-5(3H)-one 2,6,7,8,9,10-Hexahydro-10-[(2-methylphenyl)methyl]-7-(phenylmethyl)-imidazo[1,2-a]pyrido[4,3-d]pyrimidin-5(3H)-one
CAS	41276-02-2
EINECS
Chemical Formula	C24H26N4O
Molecular Weight	386.49
inchi
Package	10 mM * 1 mL;5 mg;10 mg;50 mg;100 mg
Price	Email to quote
Descriptions	TIC10 isomer TIC10 isomer MedChemExpress (MCE) HY-15615 41276-02-2 ONC201 isomer 99.91% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US Descriptions TIC10 isomer TIC10 isomer MedChemExpress (MCE) HY-15615 41276-02-2 ONC201 isomer 99.91% Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month Room temperature in continental US may vary elsewhere. TIC10 isomer is the isomer of TIC10. TIC10 isomer does not possess the reported biological activity of inducing TRIAL expression. TRAIL (TNF related apoptosis inducing ligand) is a cytokine that kills cancer cells but shows no toxicity against normal cells. TIC-10 (TRAIL inducing compound 10) (Compound 3a), is an anticancer drug first reported in a 1973 patent. The structure of TIC10 3a had been mis-assigned as TIC10 isomer (Compound 3b) in the initial patent. Subsequent synthesis of the originally reported structure by an alternate route shows TIC10 isomer (Compound 3b) does not possess the reported biological activity of inducing TRIAL expression[1]. \| \| \| \| \| \| \| \| \| \| [1]. Xin D, et al. Development of a 13C NMR Chemical Shift Prediction Procedure Using B3LYP/cc-pVDZ andEmpirically Derived Systematic Error Correction Terms: A Computational Small MoleculeStructure Elucidation Method. J Org Chem. 2017 May 19 82(10):5135-5145. [Content Brief]
Supplier Website	https://www.medchemexpress.com/TIC10-isomer.html
Last Update	2025-05-21 16:50:25

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