(S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate MedChemExpress (MCE)

Product Name	Clopidogrel hydrogen sulfate
Synonyms	Clopidogrel sulfate clopidogrel sulphate clopidogrel bisulfate Clopidogrel Bisulfate Clopidogerl Bisulfate Clopidogrel bisulphate Clopidogrel Bisulfate I Synonyms Clopidogrel sulfate clopidogrel sulphate clopidogrel bisulfate Clopidogrel Bisulfate Clopidogerl Bisulfate Clopidogrel bisulphate Clopidogrel Bisulfate I Clopidogrel Bisulfate II Clopidogrel Hydrogensulfate Clopidogrel hydrogen sulfate clopidogrel hydrogen sulphate Methyl (S)-(Chlorophenyl)(tetrahydrothienopyridinyl)acetate methyl (+)-(s)-a-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-5(4h)acetate, hydrogen sulfate salt
CAS	120202-66-6;135046-48-9;144077-07-6
EINECS
Chemical Formula	C16H18ClNO6S2
Molecular Weight	419.89
inchi	InChI=1/C15H14ClNO2S.H2O4S/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;1-5(2,3)4/h1-4,6,8,14H,5,7,9H2,(H,18,19);(H2,1,2,3,4)/t14-;/m0./s1
Package	10 mM * 1 mL;100 mg;500 mg
Price	Email to quote
Descriptions	Clopidogrel hydrogen sulfate Clopidogrel hydrogen sulfate MedChemExpress (MCE) HY-17459 120202-66-6 (S)-(+)-Clopidogrel bisulfate Descriptions Clopidogrel hydrogen sulfate Clopidogrel hydrogen sulfate MedChemExpress (MCE) HY-17459 120202-66-6 (S)-(+)-Clopidogrel bisulfate (S)-(+)-Clopidogrel hydrogen sulfate 99.43% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively. Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation．Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor. Clopidogrel (1.5 mM 12 and 24 hours) up-regulates the expression of TRIB3 and CHOP in a concentration- and time-dependent manner, as measured by real-time PCR and Western blot analysis[3]. Clopidogrel (1.5 mM 24 hours) significantly induces human gastric epithelial cell (GES-1) apoptosis[3]. Clopidogrel (5 mg/kg) significantly inhibits thrombus formation compared with vehicle. Acetylsalicylic acid (0.15 mg/kg) can add to the antithrombotic effect of Clopidogrel in mice Acetylsalicylic acid (0.6 mg/kg) blunts the antithrombotic effect of Clopidogrel[4]. CYP2B6 18.2 nM (IC50) P2Y12 Receptor CYP2C19 524 nM (IC50) \| \| \| \| \| \| \| \| \| \| [1]. Katsunobu Hagihara, et al. Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, Clopidogrel, and ticlopidine. Drug Metab Pharmacokinet. 2008 23(6):412-20. [Content Brief]* [2]. Jean-Marc Herbert, et al. P2Y12, a new platelet ADP receptor, target of Clopidogrel.Semin Vasc Med. 2003 May 3(2):113-22. [Content Brief] [3]. Hai-Lu Wu, et al. Increased endoplasmic reticulum stress response is involved in Clopidogrel-induced apoptosis of gastric epithelial cells. PLoS One. 2013 Sep 13 8(9):e74381. [Content Brief] [4]. Ran Ni, et al. Effect of Different Doses of Acetylsalicylic Acid on the Antithrombotic Activity of Clopidogrel in a Mouse Arterial Thrombosis Model.Arterioscler Thromb Vasc Biol. 2018 Oct 38(10):2338-2344. [Content Brief] [5]. Kuszynski DS, et al. Clopidogrel treatment inhibits P2Y2-Mediated constriction in the rabbit middle cerebral artery [published online ahead of print, 2021 Oct 1]. Eur J Pharmacol. 2021 174545. [Content Brief]
Last Update	2025-04-01 14:45:47

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