Pyridostigmine MedChemExpress (MCE)

Product Name	pyridostigmine bromide
Synonyms	regonal ro1-5130 Mestinon mestinonbromide mestinonebromide Pyridostigmine Bromine PYRIDOSTIGMINE BROMIDE Synonyms regonal ro1-5130 Mestinon mestinonbromide mestinonebromide Pyridostigmine Bromine PYRIDOSTIGMINE BROMIDE pyridostigmine bromide 3-dimethylcarbamoyloxy-1-methylpyridinium bromide (1-methylpyridin-1-ium-3-yl) N,N-dimethylcarbamate pyridinium,3-hydroxyl-1-methyl-,bromide,dimethylcarbamate pyridinium,3-hydroxy-1-methyl-,bromide,dimethylcarbamate(ester)
CAS	101-26-8
EINECS	202-929-9
Chemical Formula	C9H13BrN2O2
Molecular Weight	261.12
inchi	InChI=1/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
Package	10 mM * 1 mL;500 mg;1 g;5 g
Price	Email to quote
Descriptions	Pyridostigmine bromide Pyridostigmine bromide MedChemExpress (MCE) HY-B0207A 101-26-8 99.93% 4°C, stored under nitrogen In solvent : -80°C, 6 months Descriptions Pyridostigmine bromide Pyridostigmine bromide MedChemExpress (MCE) HY-B0207A 101-26-8 99.93% 4°C, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (stored under nitrogen) Room temperature in continental US may vary elsewhere. Pyridostigmine bromide is an orally active cholinesterase (ChE) inhibitor that can be used in cardiovascular disease research. Pyridostigmine bromide (10-80 ng/mL, 3-72 hours) at low concentrations (10-40 ng/mL) enhances SH-SY5Y cell activity and mitochondrial activity, while at high concentration (80 ng/mL) it inhibits cell viability[5]. Pyridostigmine bromide (60-80 ng/mL, 72 hours) promotes the accumulation of SH-SY5Y cells in the S phase[5]. Pyridostigmine bromide (40-80 ng/mL, 24 hours) upregulates the expression of the telomerase gene, p53 gene, and DNMT1 gene in SH-SY5Y cells[5]. Pyridostigmine bromide (1 or 3 mg/kg, s.c., once daily for 7 days) can reduce acetylcholinesterase activity in the blood of C57BL/6J mice[3]. Pyridostigmine bromide (30 mg/kg, p.o., once daily for one month) improves myocardial changes and reduces inflammatory responses in a Trypanosoma cruzi infection-induced chronic Chagas cardiomyopathy C57BL/6J mouse model[4]. AChE \| \| \| \| \| \| \| \| \| \| [1]. Gales BJ, et al. Pyridostigmine in the treatment of orthostatic intolerance. Ann Pharmacother. 2007 Feb 41(2):314-8. Epub 2007 Feb 6. [Content Brief] [2]. Kanjwal K, et al. Pyridostigmine in the treatment of postural orthostatic tachycardia: a single-center experience. Pacing Clin Electrophysiol. 2011 Jun 34(6):750-5. [Content Brief] [3]. Bernatova I, et al. Effect of chronic pyridostigmine bromide treatment on cardiovascular and behavioral parameters in mice[J]. Pharmacology Biochemistry and Behavior, 2003, 74(4): 901-907. [Content Brief] [4]. de Cuba MB, et al. Effects of cholinergic stimulation with pyridostigmine bromide on chronic chagasic cardiomyopathic mice. Mediators Inflamm. 2014 2014:475946. [Content Brief] [5]. Azzolin VF, et al. Effects of Pyridostigmine bromide on SH-SY5Y cells: An in vitro neuroblastoma neurotoxicity model. Mutat Res Genet Toxicol Environ Mutagen. 2017 Nov 823:1-10. [Content Brief]
Supplier Website	https://www.medchemexpress.com/pyridostigmine-bromide.html
Last Update	2025-05-21 16:50:25

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