Oxybutynin MedChemExpress (MCE)

Product Name	oxybutynin chloride
Synonyms	ditropan OXYBUTYNIN HCL Oxybutynin HCL Oxybutynine hcl OXYBUTYNIN CHLORIDE oxybutynin chloride OXYBUTYNIN HYDROCHLORIDE Synonyms ditropan OXYBUTYNIN HCL Oxybutynin HCL Oxybutynine hcl OXYBUTYNIN CHLORIDE oxybutynin chloride OXYBUTYNIN HYDROCHLORIDE Oxybutynin Hydrochloride 4-diethylamino-2-butynylphenyl(cyclohexyl)glycolatehydrochloride alpha-phenylcyclohexaneglycolicacid4-(diethylamino)-2-butynylesterhydroch cyclohexaneglycolicacid,alpha-phenyl-,4-(diethylamino)-2-butynylester,hydr A-PHENYLCYCLOHEXANEGLYCOLIC ACID 4-(DIETHYLAMINO)-2-BUTYNYL ESTER, HYDROCHLORIDE
CAS	1508-65-2
EINECS	216-139-7
Chemical Formula	C22H32ClNO3
Molecular Weight	393.95
inchi	InChI=1/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H
Package	10 mM * 1 mL;100 mg;500 mg;1 g;5 g
Price	Email to quote
Descriptions	Oxybutynin chloride Oxybutynin chloride MedChemExpress (MCE) HY-B0267A 1508-65-2 99.15% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Oxybutynin chloride Oxybutynin chloride MedChemExpress (MCE) HY-B0267A 1508-65-2 99.15% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Oxybutynin chloride is an oral active and competitive mAChR antagonist with Kis of 14.3 and 5.55 nM for specific [3H]NMS binding in the mouse bladder and cerebral cortex, respectively. Oxybutynin chloride inhibits vascular Kv channels in a manner independent of anticholinergic effect, with an IC50 value of 11.51 μM. Oxybutynin chloride reduces muscle spasm in the bladder and urinary tract, can be used in study of overactive bladder syndrome (OAB). Oxybutynin (chloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Oxybutynin chloride (0.1, 0.3, 1, 3, 10, 30, 100 μM 200 ms) inhibits vascular Kv channels in a concentration-dependent manner independent of anticholinergic effect in coronary arterial smooth muscle cells[1]. Oxybutynin chloride (27.2 mg/kg p.o. single) exhibits significant binding of mouse brain muscarinic receptors that about a 2-fold increase in Kd values for specific [3H]N-methylscopolamine binding 0.5 and 2 h later[2]. \| \| \| \| \| \| \| \| \| \| [1]. Li H, et al. The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov 46(11):1030-1036. [Content Brief] [2]. Oki T, et al. Comparative evaluation of central muscarinic receptor binding activity by oxybutynin, tolterodine and darifenacin used to treat overactive bladder. J Urol. 2007 Feb 177(2):766-70. [Content Brief]
Last Update	2025-04-01 14:45:47

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