1-Rimantadine MedChemExpress (MCE)

Product Name	Rimantadine
Synonyms	1-Adaman RiMantidine Rimantadine 1-Rimantadine 1-Adamantanethylamine RiMantadine (FluMadine) 1-(1-Adamantyl)-ethylamine Synonyms 1-Adaman RiMantidine Rimantadine 1-Rimantadine 1-Adamantanethylamine RiMantadine (FluMadine) 1-(1-Adamantyl)-ethylamine 1-Adamantan-1-ylethylamine 1-(AdaMantan-1-yl)ethanaMine 1-(adaMantan-1-yl)ethanaMine hydrochloride 2-(tricyclo[3.3.1.1~3,7~]dec-1-yl)ethanamine 1-(tricyclo[3.3.1.1~3,7~]dec-1-yl)ethanamine
CAS	13392-28-4
EINECS	1308068-626-2
Chemical Formula	C12H21N
Molecular Weight	179.3
inchi	InChI=1/C12H21N/c13-2-1-12-6-9-3-10(7-12)5-11(4-9)8-12/h9-11H,1-8,13H2
Package	10 mM * 1 mL;5 mg;10 mg;25 mg
Price	Email to quote
Descriptions	Rimantadine Rimantadine MedChemExpress (MCE) HY-B0338 13392-28-4 1-Rimantadine 99.86% -20°C, protect from light In solvent : -80°C, 6 months Descriptions Rimantadine Rimantadine MedChemExpress (MCE) HY-B0338 13392-28-4 1-Rimantadine 99.86% -20°C, protect from light In solvent : -80°C, 6 months -20°C, 1 month (protect from light) Room temperature in continental US may vary elsewhere. Rimantadine is an orally active inhibitor for M2 protein, that blocks the hydrogen ion channel activity, prevents the entry and replication of the virus, and exhibits board-spectrum antiviral activity. Rimantadine (0-10 μg/mL, 72 h) inhibits the RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells with IC50 of 6.7 and 1.6 μg/mL[1]. Rimantadine (0-10 μg/mL, 72 h) increases the expression of the autophagy marker LC3, inhibits the phosphorylation of mTOR, increases the number of lysosomes, and promotes autophagy in HAV-infected Huh7 cell[1]. Rimantadine (20-80 mg/kg/day, po for 5 days) exhibits anti-infectious activity with Oseltamivir (HY-13317) in H3N2-infected mouse models[2]. \| \| \| \| \| \| \| \| \| \| [1]. Sasaki-Tanaka R, et al., Amantadine and Rimantadine Inhibit Hepatitis A Virus Replication through the Induction of Autophagy. J Virol. 2022 Sep 28 96(18):e0064622. [Content Brief] [2]. Simeonova L, et al., Prophylactic and therapeutic combination effects of rimantadine and oseltamivir against influenza virus A (H3N2) infection in mice. Antiviral Res. 2012 Aug 95(2):172-81. [Content Brief]
Last Update	2025-04-01 14:45:47

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