Mepivacaine MedChemExpress (MCE)

Product Name	mepivacaine hydrochloride
Synonyms	Mepivacaine HCL Mepivacaine HCl USP carbocainehydrochloride mepivacaine hydrochloride dl-mepivacainehydrochloride Ropivacaine base Mepivacaine HCL Mepivacaine Hydrochloride (200 mg) Synonyms Mepivacaine HCL Mepivacaine HCl USP carbocainehydrochloride mepivacaine hydrochloride dl-mepivacainehydrochloride Ropivacaine base Mepivacaine HCL Mepivacaine Hydrochloride (200 mg) 1-methyl-2',6'-pipecoloxylididehydrochloride 1-methyl-2',6'-pipecoloxylididehydrochloride 1-methyl-2',6'-pipecoloxylidine hydrochloride dl-1-methyl-2',6'-pipecoloxylididehydrochloride 6'-pipecoloxylidide,1-methyl-2monohydrochloride 2',6'-Pipecoloxylidide, 1-methyl-, monohydrochloride (6CI, 8CI) n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamide hydrochloride n-(2,6-dimethylphenyl)-1-methyl-2-piperidinecarboxamidmonohydrochloride (1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (9CI)
CAS	1722-62-9
EINECS	217-023-9
Chemical Formula	C15H22N2O.ClH
Molecular Weight	282.81
inchi	InChI=1/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
Package	10 mM * 1 mL;500 mg;1 g;5 g
Price	Email to quote
Descriptions	Mepivacaine hydrochloride Mepivacaine hydrochloride MedChemExpress (MCE) HY-B0517A 1722-62-9 99.68% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months Descriptions Mepivacaine hydrochloride Mepivacaine hydrochloride MedChemExpress (MCE) HY-B0517A 1722-62-9 99.68% 4°C, sealed storage, away from moisture and light In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture and light) Room temperature in continental US may vary elsewhere. Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. Mepivacaine hydrochloride binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action[2]. Mepivacaine hydrochloride has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine)[3]. Mepivacaine hydrochloride displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels[4]. \| \| \| \| \| \| \| \| \| \| [1]. Froehle M, et al. ECMO for Cardiac Rescue after Accidental Intravenous Mepivacaine Application. Case Rep Pediatr. 2012 2012:491692. [Content Brief] [2]. mepivacaine hydrochloride. [3]. Burm, A.G., et al., Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers. Anesth Analg, 1997. 84(1): p. 85-9. [Content Brief] [4]. Leffler, A., J. Reckzeh, and C. Nau, Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites. Eur J Pharmacol, 2010. 630(1-3): p. 19-28. [Content Brief]
Last Update	2025-04-01 14:45:47

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