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Supplier NameMedChemExpress (MCE)
Contactsales
Tel609-228-6898
Mobile609-228-6898
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Emailsales@medchemexpress.com; tech@medchemexpress.com
Websitehttps://www.medchemexpress.com/
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Product NameNaftifine hydrochloride
SynonymsNAFTINE HCL
NAFTIFINE HCL
Naftifine HCl
NAFTIFENE HYDROCHLORIDE
NAFTIFINE HYDROCHLORIDE
Naftifine hydrochloride
Naftifine hyrdrochloride

Synonyms

NAFTINE HCL
NAFTIFINE HCL
Naftifine HCl
NAFTIFENE HYDROCHLORIDE
NAFTIFINE HYDROCHLORIDE
Naftifine hydrochloride
Naftifine hyrdrochloride
Exoderil, Naftin, Suadian,
Naftifine Hydrochloride (200 mg)
(E)-N-Cinnamyl-N-methyl(1-naphthylmethyl)amine hydrochloride
N-TRANS-CINNAMYL-N-METHYL-(1-NAPHTHYLMETHYL)AMINE HYDROCHLORIDE
CAS65473-14-5
EINECS620-502-9
Chemical FormulaC21H22ClN
Molecular Weight323.86
inchiInChI=1/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+
Package10 mM * 1 mL;25 mg;50 mg;100 mg;250 mg;500 mg;1 g
PriceEmail to quote
DescriptionsNaftifine hydrochloride

Naftifine hydrochloride

MedChemExpress (MCE)

HY-B0518A

65473-14-5

99.82%

4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months

Descriptions

Naftifine hydrochloride

Naftifine hydrochloride

MedChemExpress (MCE)

HY-B0518A

65473-14-5

99.82%

4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months
-20°C, 1 month (sealed storage, away from moisture)

Room temperature in continental US
may vary elsewhere.

Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition.

Naftifine exhibits an interesting in vitro spectrum of activity against dermatophytes (38 strains
minimal inhibitory concentration (MIC) range 0.1 to 0.2 mg/mL), aspergilli (6 strains
MIC range, 0.8 to 12.5 mg/mL), Sporothrix schenckii (2 strains
MICs, 0.8 and 1.5 mg/mL), and yeasts of the genus Candida (77 strains
MIC range, 1.5 to greater than 100 mg/mL)[1].

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[1]. Georgopoulos, A., et al., In vitro activity of naftifine, a new antifungal agent. Antimicrob Agents Chemother, 1981. 19(3): p. 386-9. [Content Brief]

[2]. Ryder, N.S., G. Seidl, and P.F. Troke, Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans. Antimicrob Agents Chemother, 1984. 25(4): p. 483-7. [Content Brief]

[3]. Parish, L.C., et al., A double-blind, randomized, vehicle-controlled study evaluating the efficacy and safety of naftifine 2% cream in tinea cruris. J Drugs Dermatol, 2011. 10(10): p. 1142-7. [Content Brief]

[4]. Gupta, A.K., J.E. Ryder, and E.A. Cooper, Naftifine: a review. J Cutan Med Surg, 2008. 12(2): p. 51-8. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/naftifine-hydrochloride.html
Last Update2025-05-21 16:50:25
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