D-(-)-α-Aminobenzylpenicillin sodium salt MedChemExpress (MCE)

Product Name	Ampicillin Na
Synonyms	Alpen-n Citteral Amcill-s omnipen-n penialmen Domicillin penbritin-s Synonyms Alpen-n Citteral Amcill-s omnipen-n penialmen Domicillin penbritin-s polycillin-n Ampicillin Na Binotalsodium Ampicillin Sodium Ampicillin Sodium oral ampicillin, sodium salt AMPICILLIN SODIUM, STERILE USP d-(-)-alpha-aminobenzylpenicillin sodium salt D-6-(-Amino-phenylacetamido)penicillanicacidsodiumsalt sodium 6-{[amino(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate sodium (2S,5R,6R)-6-{[amino(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-,sodiumsalt,d-(-)-4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid sodium (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate sodium [2s-[2alpha,5alpha,6beta(s*)]]-6-(aminophenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
CAS	69-52-3
EINECS	200-708-1
Chemical Formula	C16H18N3NaO4S
Molecular Weight	371.39
inchi	InChI=1/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/t9-,10-,11+,14-;/m1./s1
Package	10 mM * 1 mL;500 mg;1 g;5 g
Price	Email to quote
Descriptions	Ampicillin sodium Ampicillin sodium MedChemExpress (MCE) HY-B0522A 69-52-3 D-(-)-α-Aminobenzylpenicillin sodium salt 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Ampicillin sodium Ampicillin sodium MedChemExpress (MCE) HY-B0522A 69-52-3 D-(-)-α-Aminobenzylpenicillin sodium salt 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria. Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1]. Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3]. Mice: Ampicillin is dissolved in normal saline. Male C57BL/6 mice were anesthetized with halothane and subjected to bilateral common carotid artery occlusion for 40 min. Before transient forebrain ischemia, ampicillin (200 mg/kg, intraperitoneally [i.p.]) or penicillin G (6,000 U/kg or 20,000 U/kg, i.p.) was administered daily for 5 days. In the control animals, saline was administered at the same volume and time schedule[3]. β-lactam \| \| \| \| \| \| \| \| \| \| [1]. Chopra SL, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep 27(9):223-7. [Content Brief] [2]. Lund B, et al. Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin andpivampicillin. Eur J Clin Pharmacol. 1974 7(2):133-5. [Content Brief] [3]. Lee KE, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar 20(2):185-92. [Content Brief]
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Last Update	2025-05-21 16:50:25

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