YM060 MedChemExpress (MCE)

Product Name	Ramosetron Hydrochloride
Synonyms	RAMOSETRON HCL Ramosetron HCl (r)-monohydrochlorid RAMOSETRON HYDROCHLORIDE Ramosetron Hydrochloride (1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)-methanon (r)-5-((1-methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1h-benzimidazolehydr Synonyms RAMOSETRON HCL Ramosetron HCl (r)-monohydrochlorid RAMOSETRON HYDROCHLORIDE Ramosetron Hydrochloride (1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)-methanon (r)-5-((1-methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1h-benzimidazolehydr (R)-5-[(1-Methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole hydrochloride (1-methylindol-3-yl)-[(5r)-4,5,6,7-tetrahydro-3h-benzimidazol-5-yl]methanone hydrochloride
CAS	132907-72-3
EINECS
Chemical Formula	C17H18ClN3O
Molecular Weight	315.8
inchi	InChI=1/C17H17N3O.ClH/c1-20-9-13(12-4-2-3-5-16(12)20)17(21)11-6-7-14-15(8-11)19-10-18-14;/h2-5,9-11H,6-8H2,1H3,(H,18,19);1H/t11-;/m1./s1
Package	10 mM * 1 mL;50 mg;100 mg
Price	Email to quote
Descriptions	Ramosetron Hydrochloride Ramosetron Hydrochloride MedChemExpress (MCE) HY-B0595 132907-72-3 YM060 99.95% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months Descriptions Ramosetron Hydrochloride Ramosetron Hydrochloride MedChemExpress (MCE) HY-B0595 132907-72-3 YM060 99.95% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Ramosetron (YM060 free base) Hydrochloride is an orally active 5-HT3 antagonist that improves dysphoria, interference with activity and food avoidance. Ramosetron Hydrochloride is promising for research of irritable bowel syndrome with diarrhea. Ramosetron Hydrochloride (1 μM) inhibits 5-HT3 receptor-dependent 5-HT release in guinea pig colonic mucosa[3]. Ramosetron Hydrochloride (0.01-0.1 mg/kg, p.o., twice daily for 5 days) Ameliorates 5-fluorouracil (5-FU) (HY-90006)-induced intestinal mucositis in C57BL/6 mice[2]. 5-HT3 Receptor \| \| \| \| \| \| \| \| \| \| [1]. http://www.drugsupdate.com/generic/view/1111 [2]. Yasuda M, et al. 5-HT₃ receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cells. Br J Pharmacol. 2013 Mar 168(6):1388-400. [Content Brief] [3]. Kojima SI, et al. Investigation of 5-HT3 receptor-triggered serotonin release from guinea-pig isolated colonic mucosa: a role of PYY-containing endocrine cell. Eur J Pharmacol. 2017 Mar 15 799:196-200. [Content Brief] [4]. Fukudo S, et al. Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women. Gastroenterology. 2016 Feb 150(2):358-66.e8. [Content Brief]
Last Update	2025-04-01 14:45:47

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