KX1-004 MedChemExpress (MCE)

Product Name	KX1-004
Synonyms	CS-1235 KX1-004 KX1-004, 518058-84-9 5-fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxaMide 5-Fluoro-N-[(3-hydroxyphenyl)methyl]-1H-indole-2-carboxamide 5-Fluoro-N-[(3-hydroxyphenyl)methyl]-1H-indole-2-carboxamide KX1-004 Synonyms CS-1235 KX1-004 KX1-004, 518058-84-9 5-fluoro-N-(3-hydroxybenzyl)-1H-indole-2-carboxaMide 5-Fluoro-N-[(3-hydroxyphenyl)methyl]-1H-indole-2-carboxamide 5-Fluoro-N-[(3-hydroxyphenyl)methyl]-1H-indole-2-carboxamide KX1-004 KX1-004 5-Fluoro-N-[(3-hydroxyphenyl)methyl]-1H-indole-2-carboxamide
CAS	518058-84-9
EINECS
Chemical Formula	C16H13FN2O2
Molecular Weight	284.29
inchi
Package	10 mM * 1 mL;1 mg;5 mg;10 mg;25 mg;50 mg
Price	Email to quote
Descriptions	KX1-004 KX1-004 MedChemExpress (MCE) HY-18237 518058-84-9 99.75% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions KX1-004 KX1-004 MedChemExpress (MCE) HY-18237 518058-84-9 99.75% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. KX1-004 is a potent and non-ATP competitive Src-PTK inhibitor with an IC50 of 40 μM. KX1-004 protects the cochlea from hazardous noise and prevents noise-induced hearing loss (NIHL). KX1-004 (30 µM) provides significant protection against noise-induced temporary threshold shift (TTS), permanent threshold shift (PTS) and outer hair cells (OHC) loss[1]. KX1-004 (50 mg/kg) is effective against noise exposure[2]. \| \| \| \| \| \| \| \| \| \| [1]. Harris KC, et al. Prevention of noise-induced hearing loss with Src-PTK inhibitors. Hear Res. 2005 Oct 208(1-2):14-25. [Content Brief] [2]. Bielefeld EC, et al. A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing loss. Noise Health. 2005 Oct-Dec 7(29):24-30. [Content Brief]
Last Update	2025-04-01 14:45:47

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