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  6. (S)-Omeprazole potassium salt; (-)-Omeprazole potassium salt

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Supplier NameMedChemExpress (MCE)
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Product NameEsomeprazole potassium
SynonymsEsomeprazole potassium
(S)-Omeprazole potassium
(S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]
potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide

Synonyms

Esomeprazole potassium
(S)-Omeprazole potassium
(S)-5-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzo[d]
potassium,5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide
(R)-5-METHOXY-2-((4-METHOXY-3,5-DIMETHYLPYRIDIN-2-YL)METHYLSULFINYL)BENZO[D]IMIDAZOL-1-IDE POTASSIUM SALT
CAS161796-84-5
EINECS
Chemical FormulaC17H19KN3O3S
Molecular Weight384.51
inchi
Package1 mg;5 mg
PriceEmail to quote
DescriptionsEsomeprazole potassium salt

Esomeprazole potassium salt

MedChemExpress (MCE)

HY-17021B

161796-84-5

(S)-Omeprazole potassium salt

Descriptions

Esomeprazole potassium salt

Esomeprazole potassium salt

MedChemExpress (MCE)

HY-17021B

161796-84-5

(S)-Omeprazole potassium salt
(-)-Omeprazole potassium salt

98.18%

-20°C, protect from light, stored under nitrogen *The compound is unstable in solutions, freshly prepared is recommended.

Room temperature in continental US
may vary elsewhere.

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research.

Esomeprazole (25-100 µM
20 hours
MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification[1].

Esomeprazole (30-300 mg/kg
oral gavage
daily
for 19 or 11 days
C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis[2].

H+, K+-ATPase[1][2] In Vitro Esomeprazole (25-100 µM
20 hours
MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Esomeprazole potassium salt Related Antibodies Cell Viability Assay[1] Cell Line: MDA-MB-468 cells

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[1]. Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014
17(3):439-46. [Content Brief]

[2]. Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26
8:16. [Content Brief]

[3]. Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15
59(14):1333-9. [Content Brief]

Supplier Websitehttps://www.medchemexpress.com/Esomeprazole-potassium-salt.html
Last Update2025-04-01 14:45:47
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