Sulpiride MedChemExpress (MCE)

Product Name	(+-)-sulpiride
Synonyms	SP Abilit Aiglonyl R.D. 1403 SULPIRIDE rac Sulpiride (+-)-sulpiride Synonyms SP Abilit Aiglonyl R.D. 1403 SULPIRIDE rac Sulpiride (+-)-sulpiride N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxy-5-sulfamoylbenzamide N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoyl-benzamide N-[(1-ethylpyrrolidin-3-yl)methyl]-2-methoxy-5-sulfamoylbenzamide 5-(aminosufonyl)-n-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide (2R)-1-ethyl-2-({[(2-methoxy-5-sulfamoylphenyl)carbonyl]amino}methyl)pyrrolidinium (2S)-1-ethyl-2-({[(2-methoxy-5-sulfamoylphenyl)carbonyl]amino}methyl)pyrrolidinium
CAS	15676-16-1
EINECS	239-753-7
Chemical Formula	C15H23N3O4S
Molecular Weight	341.43
inchi	InChI=1/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/p+1/t11-/m1/s1
Package	10 mM * 1 mL;100 mg
Price	Email to quote
Descriptions	Sulpiride Sulpiride MedChemExpress (MCE) HY-B1019 15676-16-1 99.28% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Sulpiride Sulpiride MedChemExpress (MCE) HY-B1019 15676-16-1 99.28% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Sulpiride is an orally active dopamine D2/D3 receptor antagonist. Sulpiride is an atypical antipsychotic agent of the benzamide family. Sulpiride can be used in research into anxiety, depression and breast cancer. Dopamine, Alzheimer's, depression, Anxiety, Sprague-Dawley rats, NMRI mouse, Parkinson’s disease, psychosis, MCF-7/Adr, Breast cancer, Dexamethasone, Drug combination，MCF-7/Adr, Cancer stem-like cells (CSCs) Sulpiride (50 mg/kg Subcutaneous injection Single dose) can increase the dopamine level in Sprague-Dawley rats[2]. Sulpiride (5-20 mg/kg Intraperitoneal injection Single dose) improves memory, but induces anxiety in Parkinson's disease (PD) mice at a dose of 20 mg/kg[3]. Sulpiride (25-100 mg/kg Oral gavage Once daily for 18 days) can enhance the anti-tumor activity of dexamethasone (DEX) (HY-14648) (1 and 8 mg/kg) in combination with dexamethasone in nu/nu nude mice bearing MCF-7/Adr xenografts.Without significant toxicity to organs[4]. D2 Receptor D3 Receptor \| \| \| \| \| \| \| \| \| \| [1]. Rüther, E et al. Antidepressant action of sulpiride. Results of a placebo-controlled double-blind trial. Pharmacopsychiatry vol. 32,4 (1999): 127-35. [Content Brief] [2]. Jaworski, J N et al. Effect of dopamine D2/D3 receptor antagonist sulpiride on amphetamine-induced changes in striatal extracellular dopamine. European journal of pharmacology vol. 418,3 (2001): 201-6. [Content Brief] [3]. Zarrindast, Mohammad-Reza et al. Synergistic effect between quinpirole and L-NAME as well as sulpiride and L-arginine on the modulation of anxiety and memory processes in the 6-OHDA mouse model of Parkinson's disease: An isobologram analysis. Neurobiology of learning and memory vol. 186 (2021): 107538. [Content Brief] [4]. Li, Jian et al. Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer. Acta pharmacologica Sinica vol. 38,9 (2017): 1282-1296. [Content Brief]
Last Update	2025-04-01 14:45:47

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