Etamsylate MedChemExpress (MCE)

Product Name	etamsylate
Synonyms	e141 md141 eselin altodor etamsylate Ethamsylate diethylammonium 2,5-dihydroxybenzenesulphonate Synonyms e141 md141 eselin altodor etamsylate Ethamsylate diethylammonium 2,5-dihydroxybenzenesulphonate 2,5-dihydroxy-benzenesulfonicacicompd.withdiethylamine 2,5-DihydroxybenzenesulfonicacidcompdwithN-ethylethanamine 2,5-dihydroxybenzenesulfonicacidcompd.withn-ethylethanamine
CAS	2624-44-4
EINECS	220-090-7
Chemical Formula	C10H17NO5S
Molecular Weight	263.31
inchi	InChI=1/C6H6O5S.C4H11N/c7-4-1-2-5(8)6(3-4)12(9,10)11;1-3-5-4-2/h1-3,7-8H,(H,9,10,11);5H,3-4H2,1-2H3
Package	10 mM * 1 mL;10 mg;25 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
Price	Email to quote
Descriptions	Ethamsylate Ethamsylate MedChemExpress (MCE) HY-B1074 2624-44-4 Etamsylate 99.49% 4°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months Descriptions Ethamsylate Ethamsylate MedChemExpress (MCE) HY-B1074 2624-44-4 Etamsylate 99.49% 4°C, protect from light, stored under nitrogen In solvent : -80°C, 6 months -20°C, 1 month (protect from light, stored under nitrogen) Room temperature in continental US may vary elsewhere. Ethamsylate (Etamsylate) is an orally active anti-hemorrhagic compound. Ethamsylate inhibits biosynthesis and action of prostaglandins. Ethamsylate has the potential to maintain early hemostasis as well as restores capillary resistance. Ethamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis.. Ethamsylate (480 μM, 30 mim) prolongs lifetime of neutrophils[1]. Ethamsylate (0-100 μM, 3-8 h) inhibits migration and tubulogenesis on matrigel in endothelial cells[3]. Ethamsylate (0-100 μM, 48 h), inhibits the signaling of FGF/FGFR, decreases phosphorylation Levels of AKT and Erk1/2[3]. Ethamsylate (100 mg/kg, p.o., twice a day, three days) attenuates mutilated secondary pathogenesis and exhibits a neuroprotective role in mice of spinal cord injury[4]. \| \| \| \| \| \| \| \| \| \| [1]. Zawrotniak M, et al. Selected mucolytic, anti-inflammatory and cardiovascular drugs change the ability of neutrophils to form extracellular traps (NETs). Acta Biochim Pol. 2015 62(3):465-73. [Content Brief] [2]. Kovács L, et al. Etamsylate as inhibitor of prostaglandin biosynthesis in pregnant human myometrium in vitro. Experientia. 1981 Nov 15 37(11):1182-3. [Content Brief] [3]. Albiñana V, et al. Topically Applied Etamsylate: A New Orphan Drug for HHT-Derived Epistaxis (Antiangiogenesis through FGF Pathway Inhibition). TH Open. 2019 Jul 26 3(3):e230-e243. [Content Brief] [4]. Dolma S, et al. Ethamsylate Attenuates Mutilated Secondary Pathogenesis and Exhibits a Neuroprotective Role in Experimental Model of Spinal Cord Injury. Neuroscience. 2022 Feb 21 484:26-37. [Content Brief]
Last Update	2025-04-01 14:45:47

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