BAY-e 6975 MedChemExpress (MCE)

Product Name	Climbazole
Synonyms	MEB-6401 Diadimefon Climbazole Crinipan AD BAY MEB-6401 Climbazole 0.1 1-[(4-Chlorophenoxy)(tert-butylcarbonyl)Methyl]iMidazole Synonyms MEB-6401 Diadimefon Climbazole Crinipan AD BAY MEB-6401 Climbazole 0.1 1-[(4-Chlorophenoxy)(tert-butylcarbonyl)Methyl]iMidazole 1-(4-chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutanone 1-(4-clorophenoxy)-3,3-dimethyl-1-(imidazole-1-yl)-2-butanone 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one 1-(4-Chloro-phenoxy)-1-(2,5-dihydro-imidazole-1-yl)-3,3-dimethyl-butan-2-one
CAS	38083-17-9
EINECS	253-775-4
Chemical Formula	C15H17ClN2O2
Molecular Weight	292.76
inchi	InChI=1/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3
Package	10 mM * 1 mL;100 mg;500 mg;1 g
Price	Email to quote
Descriptions	Climbazole Climbazole MedChemExpress (MCE) HY-B1151 38083-17-9 BAY-e 6975 98.26% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions Climbazole Climbazole MedChemExpress (MCE) HY-B1151 38083-17-9 BAY-e 6975 98.26% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450. Climbazole (20?μM 48?hours) significantly decreases exosome secretion in aggressive prostate cancer (PCa) cells[1]. Climbazole (20?μM) significantly inhibits the protein concentration of Alix, and Rab27a but not nSMase2[1]. Climbazole is a potent inhibitor of exosome biogenesis and/or secretion[2]. \| \| \| \| \| \| \| \| \| \| [1]. Amrita Datta, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018 May 25 8(1):8161. [Content Brief] [2]. Y Kobayashi, et al. Climbazole is a new potent inducer of rat hepatic cytochrome P450. J Toxicol Sci. 2001 Aug 26(3):141-50. [Content Brief]
Last Update	2025-04-01 14:45:47

MedChemExpress (MCE) also provides

Thalidomide-4-O-C2-NH2

Category: Signaling Pathways
CAS: 2341840-99-9
Last Update: 2025-04-01 14:45:47

PPARα-MO-1

Category: Signaling Pathways
CAS: 810677-36-2
Last Update: 2025-04-01 14:45:47

Netupitant N-oxide

Category: Signaling Pathways
CAS: 910808-11-6
Last Update: 2025-04-01 14:45:47

MK-0812

Category: Signaling Pathways
CAS: 624733-88-6
Last Update: 2025-04-01 14:45:47

TS-011

Category: Signaling Pathways
CAS: 339071-18-0
Last Update: 2025-04-01 14:45:47

SCH 530348 sulfate

Category: Signaling Pathways
CAS: 705260-08-8
Last Update: 2025-04-01 14:45:47

BAG 956

Category: Signaling Pathways
CAS: 853910-02-8
Last Update: 2025-04-01 14:45:47

YM758

Category: Signaling Pathways
CAS: 312752-85-5
Last Update: 2025-04-01 14:45:47


Supplier Name	MedChemExpress (MCE)
Contact	sales
Tel	609-228-6898
Mobile	609-228-6898
QQ
Email	sales@medchemexpress.com; tech@medchemexpress.com
Website	https://www.medchemexpress.com/
Wechat

Request for quotation

Supplier Contact