Pimagedine hydrochloride; GER-11; Aminoguanidinium chloride MedChemExpress (MCE)

Product Name	Aminoguanidine Hydrochloride
Synonyms	amino-guanidinhydrochloride carbazamidine hydrochloride Aminoguanidine Hydrochloride Aminoguanadine hydrochloride 2-aminoguanidine hydrochloride carbazamidine monohydrochloride hydrazinecarboximidamidehydrochloride Synonyms amino-guanidinhydrochloride carbazamidine hydrochloride Aminoguanidine Hydrochloride Aminoguanadine hydrochloride 2-aminoguanidine hydrochloride carbazamidine monohydrochloride hydrazinecarboximidamidehydrochloride (diaminomethylidene)hydrazinium chloride Metformin Impurity 15(Aminoguanidine hydrochloride)
CAS	1937-19-5;16139-18-7
EINECS	217-707-7
Chemical Formula	CH7ClN4
Molecular Weight	110.54608
inchi	InChI=1/CH6N4.ClH/c2-1(3)5-4;/h4H2,(H4,2,3,5);1H
Package	10 mM * 1 mL;10 mM * 1 mL;100 mg;100 mg
Price	Email to quote
Descriptions	Aminoguanidine hydrochloride Aminoguanidine hydrochloride MedChemExpress (MCE) HY-B1041 1937-19-5 Pimagedine hydrochloride Descriptions Aminoguanidine hydrochloride Aminoguanidine hydrochloride MedChemExpress (MCE) HY-B1041 1937-19-5 Pimagedine hydrochloride GER-11 Aminoguanidinium chloride 98.0% 4°C, sealed storage, away from moisture In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Aminoguanidine hydrochloride (Pimagedine hydrochloride) is an inhibitor of diamine oxidase and nitric oxide synthase. Aminoguanidine hydrochloride has a dose-dependent inhibitory effect on apoptosis induced by Doxorubicin (HY-15142). Aminoguanidine hydrochloride has antioxidant properties. Aminoguanidine hydrochloride can be used in diabetic nephropathy research. Aminoguanidine (100, 200, 500, 1000 μM, 24 h) can reduce DOX-induced DNA damage and apoptosis in A549 cells [1]. Aminoguanidine (100 μM, 30 min) can induce ERK activation in AR42J cells and promote cell proliferation [2]. minoguanidine (50 mg/kg, Intraperitoneal injection) protects mice from CCl4-induced hepatotoxicity[3]. Aminoguanidine (200 mg/kg, Single dose intraperitoneal injection) is protective against cyclophosphamide (CP) -induced oxidative stress and kidney damage in rats[4].br/> \| \| \| \| \| \| \| \| \| \| [1]. Sabuncuoglu S. Antiapoptotic effect of aminoguanidine on doxorubicin-induced apoptosis. Mol Cell Biochem. 2014 Sep 394(1-2):129-35. [Content Brief]* [2]. Chowdhury P. Aminoguanidine (AG) Induces Induced both Pro- and Antioxidant Effect in AR42J Cells, a Rat Pancreatic Tumor Cell Line. Ann Clin Lab Sci. 2017 Sep 47(5):572-580. PMID: 29066484. [Content Brief] [3]. Al-Shabanah OA, et al. Protective effect of aminoguanidine, a nitric oxide synthase inhibitor, against carbon tetrachloride induced hepatotoxicity in mice. Life Sci. 2000 66(3):265-70. [Content Brief] [4]. Abraham P, et al. Protective effect of aminoguanidine against cyclophosphamide-induced oxidative stress and renal damage in rats. Redox Rep. 2011 16(1):8-14. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Aminoguanidine-hydrochloride.html
Last Update	2025-05-21 16:50:25

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