Buspirone MedChemExpress (MCE)

Product Name	buspirone hydrochloride
Synonyms	axoren bespar buspinol BUSPIRONE HCL Buspirone HCl Buspar hydrochloride Buspiron hydrochloride Synonyms axoren bespar buspinol BUSPIRONE HCL Buspirone HCl Buspar hydrochloride Buspiron hydrochloride buspirone hydrochloride 1-cyclopentanediacetimide,n-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-h 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-9-dione 1-[4-(7,9-dioxo-8-azaspiro[4.5]dec-8-yl)butyl]-4-(pyrimidin-2-yl)piperazin-1-ium 8-[4-[4-(2-pyrimidinyl)-1-piperazin-1-iumyl]butyl]-8-azaspiro[4.5]decane-7,9-dione 8-[4-[4-(2-PYRIMIDINYL)-1-PIPERAZINYL]BUTYL]-8-AZASPIRO[4,5]DECANE-7,9-DIONE HYDROCHLORIDE
CAS	33386-08-2
EINECS	251-489-4
Chemical Formula	C21H32ClN5O2
Molecular Weight	421.96
inchi	InChI=1/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2/p+1
Package	10 mM * 1 mL;10 mM * 1 mL;100 mg;100 mg
Price	Email to quote
Descriptions	Buspirone hydrochloride Buspirone hydrochloride MedChemExpress (MCE) HY-B1115 33386-08-2 99.99% 4°C, sealed storage, away from moisture In solvent : -80°C, 1 year Descriptions Buspirone hydrochloride Buspirone hydrochloride MedChemExpress (MCE) HY-B1115 33386-08-2 99.99% 4°C, sealed storage, away from moisture In solvent : -80°C, 1 year -20°C, 6 months (sealed storage, away from moisture) Room temperature in continental US may vary elsewhere. Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research. Buspirone hydrochloride (0-400 μg/mL 6 hours) has cytotoxic effect in Lymphocytes[1].Buspirone hydrochloride (0-180 μg/mL 0-3 hours Lymphocytes) induces ROS formation, MMP collapse, lipid peroxidation, lysosomal damage and elevation of glutathione disulfide (GSSG)[1]. Buspirone hydrochloride (1-5 mg/kg i.p. and i.g. for 5 days C57BL/6N mice) reduces anxiety/depression behaviors[2].?Buspirone hydrochloride (1-5 mg/kg i.p. and i.g. for 5 days C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota[2]. \| \| \| \| \| \| \| \| \| \| [1]. Salimi A, et, al. Analysis of Toxicity Effects of Buspirone, Cetirizine and Olanzapine on Human Blood Lymphocytes: in Vitro Model. Curr Clin Pharmacol. 2018 13(2):120-127. [Content Brief] [2]. Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17 11(1):6094. [Content Brief]
Supplier Website	https://www.medchemexpress.com/Buspirone-hydrochloride.html
Last Update	2025-05-21 16:50:25

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