2'-C-Methylcytidine MedChemExpress (MCE)

Product Name	2'-C-Methylcytidine
Synonyms	NM-107 VALOPICITABINE -C-Methylcytidine 2''-METHYLCYTIDINE 2'-C-METHYLCYTIDINE 2'-C-Methylcytidine 2'-CMethyl-D-cytidine Synonyms NM-107 VALOPICITABINE -C-Methylcytidine 2''-METHYLCYTIDINE 2'-C-METHYLCYTIDINE 2'-C-Methylcytidine 2'-CMethyl-D-cytidine cytidine, 2'-C-methyl- 2'-C-Methyl-1-β-D-ribofuranosylcytosine 1-(2-C-Methyl-β-D-ribofuranosyl)cytosine
CAS	20724-73-6
EINECS	200-001-2
Chemical Formula	C10H15N3O5
Molecular Weight	257.24
inchi	InChI=1/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1
Package	10 mM * 1 mL;10 mM * 1 mL;5 mg;5 mg;10 mg;10 mg;50 mg;50 mg;100 mg;100 mg
Price	Email to quote
Descriptions	NM107 NM107 MedChemExpress (MCE) HY-10468 20724-73-6 2'-C-Methylcytidine 99.23% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US Descriptions NM107 NM107 MedChemExpress (MCE) HY-10468 20724-73-6 2'-C-Methylcytidine 99.23% Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year Room temperature in continental US may vary elsewhere. NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM. NM107 (25 μM 24 hours Huh7-1 cells and cell culture-propagated HCV) treatment decreases extracellular viral titers and intracellular RNA levels. HCV[1] Cellular Effect Cell Line Type Value Description References \| \| \| \| \| \| \| \| \| \| [1]. Mathy JE, et al, Combinations of cyclophilin inhibitor NIM811 with hepatitis C Virus NS3-4A Protease or NS5B polymerase inhibitors enhance antiviral activity and suppress the emergence of resistance. Antimicrob Agents Chemother. 2008 Sep 52(9):3267-75. [Content Brief] [2]. Guedj J, et al. Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life. Proc Natl Acad Sci U S A. 2013 Mar 5 110(10):3991-6. [Content Brief]
Last Update	2025-04-01 14:45:47

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